calcifying epithelial odontogenic tumor is a rare odontogenic neoplasm. its occurrence in the maxillary sinus is very rare. maxillary tumors tend to be locally aggressive and may rapidly involve the surrounding vital structures.  we report a case of calcifying epithelial odontogenic tumor involving maxillary sinus in a 48 years old female patient with the oral mucosal involvement. the purpose o...

purpose: to report two cases of secondary epithelial iris cyst (seic) with pus-like precepitates in the cyst. patients and findings: two young men with history of penetrating trauma to the eye and primary repair developed secondary epithelial iris cyst several years later. slit-lamp biomicroscopy revealed a large cyst originating from the site of the laceration. the cyst was filled with pus-lik...

primary splenic cyst is a rare entity and majority of the cases are classified as epithelial cysts. they are uncommon, comprising only about 10% of benign non-parasitic cysts. most of the cysts are asymptomatic, and they are incidental findings during abdominal ultrasonography. we report a case of 20 years old male who presented with 1 year history of mild abdominal pain and left upper quadrant...

Clinical studies suggest that the injectable contraceptive medroxyprogesterone acetate (MPA) increases susceptibility to infections such as HIV-1, unlike the injectable contraceptive norethisterone enanthate (NET-EN). We investigated the differential effects, molecular mechanism of action and steroid receptor involvement in gene expression by MPA as compared to NET and progesterone (P4) in the ...

PURPOSE In human subjects and animal models with acute and chronic lung injury, the bioactive lysophosphatidylcholine (LPC) is elevated in lung lining fluids. The increased LPC can promote an inflammatory microenvironment resulting in lung injury. Furthermore, pathological lung conditions are associated with upregulated phospholipase A2 (PLA2), the predominant enzyme producing LPC in tissues by...

Neutrophils play an important role in innate immunity by defending the host organism against invading microorganisms. Antimicrobial activity of neutrophils is mediated by release of antimicrobial peptides, phagocytosis as well as formation of neutrophil extracellular traps (NET). These structures are composed of DNA, histones and granular proteins such as neutrophil elastase and myeloperoxidase...

A case is reported of an intracardiac 'epithelial heterotopia' with a predominant mesenchymal component. This is thought to have resulted from the differentiation of aberrant primitive cell(s) displaced into the heart during its development. Though microscopically resembling a myxoma, this lesion is clearly distinguished by the presence of glandular structures. The myxoid component exhibited a ...

Oncocytomas are benign salivary gland tumors composed of oncocytes, cuboidal to columnar epithelial cells with abundant eosinophilic cytoplasm secondary to the accumulation of excessive number of mitochondria. In 1894, the German pathologist Hurth cells in normal canine thyroid glands, while the term "Oncocyte" was coined by Hamperl in 1931. Fine Needle Aspiration Cytology salivary gland lesion...

To investigate the possibility that mesenchyme can alter the neoplastic properties of an established carcinoma, small (0.5-mm cubes) pieces of the Dunning prostatic adenocarcinoma (DT) were grown in association with seminal vesicle mesenchyme (SVM) for 1 mo. Differentiated DT epithelial cells harvested from the resultant tissue recombinants (rSVM+DT) were recombined with fresh SVM to generate 2...

To investigate the possibility that mesenchyme can alter the neoplastic properties of an established carcinoma, small (0.5-mm cubes) pieces of the Dunning prostatic adenocarcinoma (DT) were grown in association with seminal vesicle mesenchyme (SVM) for 1 mo. Differentiated DT epithelial cells harvested from the resultant tissue recombinants (1 degree SVM + DT) were recombined with fresh SVM to ...