Benign and malignant neoplasm of myoepithelial cells comprise a rare but well-characterized group of tumors in the salivary glands, breasts, and soft tissues. Histopathologically, myoepitheliomas show solid, reticular, trabecular architecture and myxoid or hyaline stroma, and are composed of round/epithelioid or spindle cells. The tumor cells of myoepitheliomas possess the capacity for epitheli...

Kim CH, et al. Thorax 2017;0:1–2. doi:10.1136/thoraxjnl-2017-211155 An 83-year-old woman presented to our emergency department with mild dyspnoea. The patient had been in her usual state of health until 3 days prior to admission. Her medical history revealed no specific illness, and she was a never-smoker. The patient’s vital signs were within normal range, and physical examination revealed dec...

Four cases of epithelial-myoepithelial carcinoma of the salivary glands arose as painless masses in patients over 60 years old, three in the parotid and one in the submandibular gland. Histologically, all the tumours were composed of small ducts with a double cell lining surrounded by a basement membrane. The inner cells were epithelial and the outer cells myoepithelial, the latter usually poss...

We report a rare case of epithelial-myoepithelial carcinoma (EMC) of the parotid gland. A 70-year-old man presented with a 4-months-history of right-sided subauricular swelling. Computed tomographic scans revealed a well-defined mass with cystic lesion, measuring about 40 mm in diameter, in the right parotid gland. Because the tumor occupied superficial lobe, he underwent superficial parotidect...

The occurrence of a second malignant neoplasm (SMN) in patients who have been submitted to kidney transplantation is increasing and causes concern; parotid carcinoma is rarely reported after transplantation and may be related to long-term chemotherapy.Salivary gland carcinomas displaying exclusively myoepithelial differentiation-myoepithelial carcinomas (EMC) are rare, being less than 1% of all...

The role of the neurohypophyseal peptide oxytocin (OT) and its receptor (OTR) in the breast has been described mainly in relation to breast feeding or to neoplastic growth regulation. We demonstrate here the presence of OT synthesis within the breast under both physiological and neoplastic conditions. In order to clarify whether normal epithelial and myoepithelial cells could synthesize OT, the...

AIMS Epithelial-myoepithelial carcinoma (EMC) is a rare malignant salivary gland neoplasm that most commonly occurs in the parotid gland, but can also arise in the minor salivary glands. Three cases are reported of epithelial-myoepithelial carcinoma of the minor salivary glands, with the goal of better defining this entity. PATIENTS AND METHODS All three cases showed a characteristic nodular/...