A molecular-mechanics computational study is performed in order to analyze the arrangement of (1R,2S)-(-)-ephedrine molecules within the 12-MR channels of the AFI aluminophosphate microporous framework and the influence on the spatial distribution of dopants embedded in the tetrahedral network. Results showed that ephedrine molecules arrange exclusively as dimers by π-π stacking of the aromatic...

mono-brominated-propyphenazone was used as a derivatization reagent for the detection and quantification of ephedrine by high performance liquid chromatography using Zorbax-XDB C18 column, and 0.02 M sodium acetate (pH 4.4): acetonitrile (52:48 v/v) as mobile phase and UV detection at 280nm. The cited reagent reacts with the secondary amino group of ephedrine in acetone using anhydrous potassiu...

CONTEXT Ephedra and ephedrine sometimes are used for weight loss or enhanced athletic performance, but the efficacy and safety of these compounds are uncertain. OBJECTIVE To assess the efficacy and safety of ephedra and ephedrine used for weight loss and enhanced athletic performance. DATA SOURCES We searched 9 databases using the terms ephedra, ephedrine, adverse effect, side effect, effic...

BACKGROUND The purpose of the study was to investigate the effect of bolus and the combination of bolus and infusion of ephedrine on maternal hypothermia which are used for treating maternal hypotension under spinal anaesthesia. PATIENTS AND METHODS 110 ASA I-II patients who developed maternal hypotension were included into the study. Spinal anaesthesia was performed with 12.5 mg heavy bupiva...

UNLABELLED This quantitative systematic review compared the efficacy and safety of ephedrine with phenylephrine for the prevention and treatment of hypotension during spinal anesthesia for cesarean delivery. Seven randomized controlled trials (n = 292) were identified after a systematic search of electronic databases (MEDLINE, EMBASE, The Cochrane Controlled Trials Registry), published articles...

STUDY OBJECTIVE To evaluate the hemodynamic effects of an intravenous (IV) ephedrine bolus given simultaneously with spinal anesthesia for cesarean delivery. DESIGN Randomized, prospective, double-blind study. SETTING Tertiary-care academic medical center. PATIENTS 40 ASA physical status I and II nonlaboring women undergoing elective cesarean delivery of term, uncomplicated, singleton pre...

BACKGROUND During caesarean section spinal anesthesia may provoke maternal hypotension that we prevent by administration of phenylephrine and/or ephedrine. Phenylephrine is however reported to reduce the near infrared spectroscopy-determined frontal lobe oxygenation (ScO2) but whether that is the case for patients exposed to spinal anesthesia is not known. OBJECTIVES To evaluate the impact of...

Effect of ephedrine in ketotic hypoglycaemia. The effect of oral ephedrine administration on a child with ketotic hypoglycaemia who had not responded to dietary measures alone was studied. After ephedrine administration, the hypoglycaemia developing after ketogenic stress was less profound and was substantially delayed. The impaired glycaemic response to glucagon during hypoglycaemia, character...

A bacterium utilizing the alkaloid (-)-ephedrine as its sole source of carbon was isolated by an enrichment-culture technique from soil supplemented with 4-benzoyl-1,3-oxazolidinon-(2). The bacterium was indentified as Pseudomonas putida by morphological and physiological studies. The following metabolites were isolated from the culture fluid: methylamine, formaldehyde, methylbenzoylcarbinol (2...