Homing of endothelial progenitor cells (EPC) to the ischemic tissues is a key event in neovascularization and tissue regeneration. In response to ischemic insult, injured tissues secrete several chemo-cytokines, including stromal cell-derived factor-1α (SDF-1α), which triggers mobilization and homing of bone marrow-derived EPC (BMD-EPC). We previously reported that SDF-1α-induced EPC homing is ...

Picarro WS-CRDS-based analyzers are the first instruments to combine simple, turnkey operation with sensitivity and precision better than or equal to the IRMS (isotope ratio mass spectrometer) systems traditionally used in stable isotope labs. This opens the door for widespread exploitation of stable isotope studies in fields such as carbon/water cycle research, GHG (greenhouse gas) monitoring,...

Aging is associated with an increased risk for atherosclerosis. A possible cause is low numbers and dysfunction of endothelial progenitor cells (EPC) which insufficiently repair damaged vascular walls. We hypothesized that decreased levels of insulin-like growth factor-1 (IGF-1) during age contribute to dysfunctional EPC. We measured the effect of growth hormone (GH), which increases endogenous...

Nowadays, most process modelling tools implement popular modelling languages such as the Business Process Model and Notation (BPMN) or the Event-driven Process Chain (EPC). However, in contrast to BPMN, no effort has yet been undertaken to standardize the EPC language, thus rendering EPCs as being merely a de-facto standard for business process modelling. Subsequently, this paper addresses this...

Title of Document: THE EFFECT OF THROMBIN ON ENDOTHELIAL PROGENITOR CELLS WITH EXERCISE AND EXERCISE TRAINING. Michael Morley Lockard, Ph.D., 2009 Directed By: Professor James Hagberg, Ph.D. Department of Kinesiology BACKGROUND: Circulating number of endothelial progenitor cells (EPCs) and EPC colony forming units (EPC-CFUs) have emerged as valuable predictors of cardiovascular health. Improvem...

OBJECTIVES Epilepsia partialis continua (EPC) is characterized by localized continuous jerks, from time to time with spreading Jacksonian seizures and, more rarely, secondarily generalized tonic-clonic seizures. EPC has numerous possible etiologies. In this paper we describe EPC in the tick-borne Russian spring-summer encephalitis (TBRSSE) and compare it with Rasmussen syndrome. METHODS AND M...

OBJECTIVE Hypertension and hypercholesterolemia might interfere with renal repair mechanisms. We hypothesized that simvastatin improves the survival of endothelial progenitor cells (EPC) in the renal microenvironment imposed by concurrent renovascular hypertension and dietary hypercholesterolemia (HTC). METHODS AND RESULTS Pigs were studied after 12 weeks of no intervention (n=6), HTC (n=6), ...

The objective of this study was to evaluate the influence of bull excretory products on the resumption of postpartum luteal function in primiparous, restricted-suckled cows. Hypotheses tested were that resumption of luteal function or proportions of cows that initiate luteal cycling did not differ among cows exposed to a bull (BE), exposed to excretory products of bulls (EPB), not exposed to a ...

A newly introduced compound, EPC-K1, represents a phosphate diester linkage of vitamin E and vitamin C. The effect of EPC-K1 on the reperfusion injury was evaluated in a heterotopic cardiac transplantation model using syngenic combination rats. Prior to the warm ischemia, 12mg EPC-K1/kg was administered intravenously to donor rats. After 15 min of warm ischemic time, hearts were harvested and p...