BACKGROUND Patient-reported outcome (PRO) instruments are important tools for monitoring disease activity and response to treatment in clinical trials and clinical practice. In recent years, there have been movements away from traditional pen-and-paper PROs towards electronic administration. When using electronic PROs (ePROs), evidence that respondents complete ePROs in a similar way to their p...

OBJECTIVES The interpretation of studies on quality of life (QoL) after lung surgery is often difficult owing to the use of multiple instruments with inconsistent scales and metrics. Although a more standardized approach would be desirable, the most appropriate instrument to be used in this setting is still largely undefined. The aim of the study was to assess the respective ability of two vali...

background: health?related quality of life (hrql) and voice handicap index (vhi) of laryngectomies seem to be relevant regarding voice rehabilitation. the aim of this study is to assess the impact on hrql and vhi of laryngectomies, following voice rehabilitation. materials and methods: a retrospective study done at the ear, nose, and throat department of the emergency county hospital. sixty?fiv...

PURPOSE The European Organization for Research and Treatment of Cancer (EORTC) scoring system and risk table were introduced in the 2008 European Association of Urology guidelines on TaT1 bladder cancer. We compared the recurrence and progression rate between EORTC risk tables and author's patients who underwent transurethral resection of bladder cancer (TURB) following intravesical Bacillus Ca...

• Patient-reported outcome (PRO) instruments used to assess QoL among patients with recurrent GBM included the European Organisation for Research and Treatment of Cancer (EORTC) Core Quality of Life Questionnaire (QLQ-C30), the EORTC QLQ Brain Cancer Module (EORTC QLQBN20), the Functional Assessment of Cancer Therapy (FACT)–General (FACT-G), the FACT–Brain (FACT-Br), and the 36-Item Short-Form ...

METHODS: This multi-center cross-sectional survey study included women who had been randomly selected from a 10-year cohort and who had previously undergone a mastectomy for breast cancer either followed by an autologous-BR, an implantBR or who had not undergone BR. These women were asked to complete the reconstruction module of the Breast-Q, the EORTC-C30 and EORTCBR23 quality of life question...

PURPOSE To assess the effects of ruxolitinib on symptom burden and quality of life (QoL) and to evaluate the ability of the modified Myelofibrosis Symptom Assessment Form (MFSAF) v2.0 to measure meaningful changes in myelofibrosis-related symptoms in patients with myelofibrosis. PATIENTS AND METHODS COMFORT-I (Controlled Myelofibrosis Study With Oral JAK Inhibitor Treatment-I) is a double-bli...

OBJECTIVE To further evaluate the higher order measurement structure of the European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire Core 30 (QLQ-C30), with the aim of generating a summary score. STUDY DESIGN AND SETTING Using pretreatment QLQ-C30 data (N = 3,282), we conducted confirmatory factor analyses to test seven previously evaluated higher order...

BACKGROUND The European Organisation for Research and Treatment of Cancer (EORTC) quality of life colorectal questionnaire module (QLQ-CR38) was developed in 1999, and an update, the QLQ CR29 was published recently. To date the Danish version of the questionnaire has not been validated. The aim of this study was to examine the psychometric properties of the Danish version of EORTC QLQ-CR38. M...

BACKGROUND The purpose of this study was to evaluate the individualized and standardized quality of life (QL) and psychological distress of patients participating in a Phase I trial of the novel therapeutic reovirus (Reolysin). METHODS 16 patients with incurable metastatic cancer were interviewed prior to being accepted into the phase I trial with a semi-structured expectations interview, the...