The regulated turnover of endoplasmic reticulum (ER)-resident membrane proteins requires their extraction from the membrane lipid bilayer and subsequent proteasome-mediated degradation. Cleavage within the transmembrane domain provides an attractive mechanism to facilitate protein dislocation but has never been shown for endogenous substrates. To determine whether intramembrane proteolysis, spe...

Abstract Sugarcane bagasse is the major by‐product of sugarcane industry, and it can serve as a substrate for biotechnological processes obtaining value‐added products. This study gave multiple adding values to using in two separate bioprocesses. was used enzymatic cocktail production from Auricularia fuscosuccinea LBM 244 source proteins phenolic compounds. A . enzyme cocktail‐assisted extract...

Ginger is one of the commonly used spices that has been exhibited to have pharmaceutical activities. These therapeutic properties are mainly attribute to gingerols and shogaols. To extract these bioactive compounds, subcritical water extraction (SWE) was employed as a green method. The influence of adding co-solvents, temperature, retention time and particle size on extraction yield were invest...

The present study was aimed at the development of a somoclonal variant and isozyme marker for Phyllanthus amarus Schum & Thonn using inter-nodal segments and the enzyme peroxidase. Maximum callus proliferation was obtained on Murashige and Skoog’s medium supplemented (MS) with 1.0 mg/l of 2,4-Dichlorophenoxyacetic acid. Three weeks-old pale yellowish white semi-friable callus was used for organ...

background homocysteine is a sulfur-containing amino acid which formed (mainly in the liver) during the metabolism of methionine. prior studies indicated the important role of hyperhomocysteinemia in pathogenesis and progression of alcoholic liver disease, liver steatosis and cirrhosis. one of the most important mechanisms by which homocysteine promote the development of hepatic injury is oxida...

Several investigations have proven the presence of anthocyanins in different parts açai plants. These compounds are responsible for notable therapeutic properties such as antioxidant, antimicrobial, anti-inflammatory, anticancer, and anticonvulsant. We therefore optimized an enzyme-assisted extraction method found açai, to be subsequently applied many fields agrifood, medicine, or cosmetics. A ...

From times immemorial, colorants, and flavorings have been used in foods. Color and flavor are the major attributes to the quality of a food product, affecting the appearance and acceptance of the product. As a consequence of the increased demand of natural flavoring and colorant from industries, there is a renewed interest in the research on the composition and recovery of natural food flavors...