escherichia coli (e. coli) is a normal inhabitant of the gastrointestinal tract of vertebrates, including humans. phylogenetic analysis has shown that e. coli is composed of four main phylogenetic groups (a, b1, b2 and d). group a and b1 are generally associated with commensals, whereas group b2 is associated with extra-intestinal pathotypes. most enteropathogenic isolates, however, are assigne...

infectious diseases are responsible for thousands of worldwide early death .many commercial antibiotics have been used to control human's infectious diseases all over the world. calotropis procera linn a wild growing plant of asclepiadaecae family is known to possess multifarious medicinal properties. total 80 non repetitive clinical e. coli strains recovered during 7 month, and were screened f...

background uropathogenic escherichia coli (upec) is a causative agent of most of urinary tract infections (utis), which expresses a multitude of virulence factors. objectives the aim of this study was to investigate virulence associated characteristics characteristics in upec isolates derived from urine specimens, and to investigate the distribution of the pathogenicity islands virulence marker...

background : enteroaggregative e. coli (eaec) is increasingly recognized as a cause of often persistent diarrhea in children and adults in both developing and developed countries. the aim of the present study was to investigate the presence and the frequency of eaec as etiologic agent of diarrhea in shiraz. methods : a total of 715 stool samples were collected from patients with diarrhea in shi...

background: the current study aimed to determine the effect and properties of surface-modified copper doped cu:zno nps on killing curves of bacterial pathogens. m ethods:   preparation  of   in  situ   surface-modified  copper  doped  zno nanoparticles (cu:zno nps) was done according to standard procedure.assay for antimicrobial activity of cu:zno nps against bacterial pathogens was carried out...

background : the emergence and increase in the incidence of extended-spectrum beta lactamase (esbl) producing escherichia coli has become an emerging challenge especially in hospitalized patients with uti. the aim of the present study was to survey the frequency of bla ctx-m genotype in esbl producing e. coli isolated from hospitalized patients with uti and determination of their antibiotic res...

background: the criteria for the quality control of iranian fresh produce are the total microbial count, enterococcal count and the detection of escherichia coli. the aim of this study was to assess microbial contamination of fresh vegetable and salad samples consumed in tehran, iran. methods: from may to october 2013, freshly vegetable (n=100) and salads (n=100) samples were randomly collected...

conclusions this is the first report of expression of cmv cp gene in iran, which is important for the preparation of anti-cmv antibody and paving the way for the use of the virus coat protein as a nanomaterial. results the identity of the expressed protein was confirmed by immunoassays such as western blot, dot-immunobinding assay (diba) and enzyme-linked immunosorbent assay (elisa) by the use ...

background and purpose: brain-derived neurotrophic factor (bdnf) is present in the hippocampus and cerebral cortex in high concentrations and has an important role in development, maintenance and regeneration of the nervous system. the aim of this study was to produce active bdnf in e.coli using transforming plasmid. methods: to construct an expression plasmid of bdnf, a gene coding for it was ...