Kun-jiao Zeng, Yohei Doi, Sandip Patil, Xi Huang, Guo-Bao Tian Program of Immunology, Institute of Human Virology, Institute of Tuberculosis Control, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China; Key Laboratory of Tropical Diseases Control (Sun Yat-sen University), Ministry of Education, Guangzhou, China; Division of Infectious Diseases, University of Pittsburgh Medica...

Enterobacter cloacae is not a primary human pathogen but has been considered to be an important cause of nosocomial infections. Even so, there are almost no reports on its ability to produce recognized virulence-associated properties. In this study, we show that most of the E. cloacae strains examined were resistant to serum bactericidal activity and were able to produce aerobactin and mannose-...

OBJECTIVES To study the incidence, antimicrobial susceptibility pattern, age and sex distribution, mortality and prognostic factors in cases of Enterobacter bacteremia. METHODS A total of 18,745 indoor patients with suspected bacteremia were included in study. Enterobacter spp were identified and speciated using standard protocols. Antimicrobial susceptibility testing was done using Stoke's d...

The activity of azlocillin and mezlocillin, new semisynthetic ureido penicillins, was investigated and compared with that of other known beta-lactam antibiotics. At a concentration of 25 mug/ml, azlocillin inhibited 74% of Enterobacter, 97% of Proteus mirabilis, 64% of Citrobacter, 91% of Pseudomonas aeruginosa, and 82% of Bacteroides strains tested. Mezlocillin inhibited 86% of Shigella, 96% o...

The taxonomy of Enterobacter species is rapidly changing. Herein we report a bloodstream infection isolate originally identified as Enterobacter cloacae by Vitek2 methodology that we found to be Kosakonia radicincitans using genetic means. Comparative whole genome sequencing of our isolate and other published Kosakonia genomes revealed these organisms lack the AmpC β-lactamase present on the ch...

Previous studies have shown that the members of the Enterobacter cloacae complex are difficult to differentiate with biochemical tests and in phylogenetic studies using multilocus sequence analysis, strains of the same species separate into numerous clusters. There are only a few complete E. cloacae genome sequences and very little knowledge about the mechanism of pathogenesis of E. cloacae on ...

Many attempts, based on biochemical properties, have been made to differentiate strains of the tribe Eschericheae-a biochemically heterogeneous collection of the Enterobacteriaceae-into genera. In the sixth edition of Bergey's Manual (Breed et al., 1948), these strains, if of animal origin, are classified into three genera: Escherichia, Aerobacter, and Klebsiella. The genus Aerobacter is subdiv...

The literature on the antagonistic action of members of the genus Aerobacter is rather scanty. Winslow and Cohen (1918a, 1918b) reported that when a mixture of 46 per cent BaciUus aerogenes cells and 54 per cent Bacillus coli cells suspended in unsterilized tap water was stored 60 days, only 29 per cent of the remaining cells were B. coli. A slight degree of antagonism might conceivably have ex...