Fusarium head blight (FHB) is a fungal disease of cereals including wheat, which results in significant economic losses and reductions grain quality. Additionally, the presence spp. productions mycotoxins/metabolites, some are toxic low concentrations. The liquid chromatography with tandem mass spectrometry (LC-MS/MS) method was applied to 216 wheat samples from field conditions diseased FHB. D...

Changes in environmental stress impact on secondary metabolite (SM) production profiles. Few studies have examined targeted SM production patterns in relation to interacting environmental conditions in stored cereals. The objectives were to examine the effect of water activity (aw; 0.95-0.90) x temperature (10-25 °C) on SM production on naturally contaminated stored wheat and that inoculated wi...

In this study, a rapid multi-mycotoxin approach was developed for biomonitoring and quantification of 27 important mycotoxins and mycotoxin metabolites in human blood samples. HPLC-MS/MS detection was used for the analysis of dried serum spots (DSS) and dried blood spots (DBS). Detection of aflatoxins (AFB1, AFB2, AFG1, AFG2, AFM1), trichothecenes (deoxynivalenol, DON; DON-3-glucoronic acid, DO...

Mycotoxin contamination in agro-food systems has been a serious concern over the last few decades in China, where the Ministry of Health has set maximum limits for mycotoxins in different agro-products. Overall survey data show that aflatoxin contamination in infant cereals, edible oils, raw milk, ginger and its related products are far below Chinese regulatory limits. The absence of aflatoxin ...

Investigations of the effects of valinomycin on mitochondria" 2 led to the discovery of antibiotic-mediated ion transport.3 Subsequent work revealed that this property is shared by valinomycin, the enniatins, the macrolide actins, and the gramicidins, including an extensive array of natural and synthetic analogues.4-6 Passive ion permeability effects have been reported obtained with these agent...