Endometriosis is the condition where endometrium gets implanted and flourishes outside the uterine cavity, most commonly in ovary and on the peritoneum which lines the abdominal cavity and viscera. Endometrial cells in areas outside the uterus are influenced by hormonal changes and respond in a way similar to the endometrium inside the uterus. Symptoms often worsen with the menstrual cycle. We ...

INTRODUCTION Developmental cysts are the most common retrorectal cystic lesions in adults, whereas reports of endometrioid cysts in this anatomic location are extremely rare. CASE PRESENTATION A 21-year-old nulliparous Greek woman presented with chronic noncyclic pelvic pain, and a retrorectal cyst was diagnosed. The lesion was resected through a laparotomy and, on histologic examination, was...

INTRODUCTION Despite extensive research endometriosis is an area with important controversies. The European Society of Human Reproduction and Embriology issued in 2014 the last Guideline for endometriosis management including the statement that among 83 recommendations in 32 cases the best available evidence was only based on good clinical practice, further research being necessary to solve the...

PURPOSE Mural nodules and papillary projections can be seen in benign ovarian endometriosis (OE) and malignant transformation of OE (endometriosis-associated ovarian cancer [EAOC]), which can pose a challenging diagnostic dilemma to clinicians. We identify the preoperative imaging characteristics helpful to the differential diagnosis between benign OE with mural nodules and EAOC. MATERIALS AN...

Aberrant up-regulation of aromatase in eutopic endometrium and implants from women with endometriosis has been reported. Aromatase induction may be mediated by increased cyclooxygenase-2 (COX-2). Recently, we demonstrated that progesterone receptor (PR)-A and PR-B serve an antiinflammatory role in the uterus by antagonizing nuclear factor kappaB activation and COX-2 expression. PR-C, which anta...

OBJECTIVE To generate and validate symptom-based models to predict endometriosis among symptomatic women prior to undergoing their first laparoscopy. DESIGN Prospective, observational, two-phase study, in which women completed a 25-item questionnaire prior to surgery. SETTING Nineteen hospitals in 13 countries. PATIENT(S) Symptomatic women (n = 1,396) scheduled for laparoscopy without a p...

Compared with ultrasound, MRI has limited indications in evaluation of Female Infertility. Laparoscopy is the gold standard for the diagnosis of pelvic endometriosis. MRI is helpful in determining the extent of deep infiltrating endometriosis, especially when laparoscopic inspection is limited by adhesions. MRI allows for much more anatomic detail as well as better measurements of uterine fibro...

Objective: The efficiency and safety of laparoscopic surgery in the management of ovarian dermoid cyst. Material and Methods: Our study included forty patients with diagnosis of unilateral or bilateral dermoid cysts between August 2006 and May 2008 underwent laparoscopic removal of dermoid cysts. All cases were performed at department of obstetrics and Gynecology, women's health centre, Faculty...

The aim of this study was to investigate the role of redox status in endometriosis and its malignant transformation. A search was conducted between 1990 and 2014 through the English language literature (online MEDLINE PubMed database) using the keywords endometriosis combined with malignant transformation, oxidative stress, and antioxidant defense. In benign endometriosis, autoxidation and Fent...

E ndometriosis is defined as a growth of ectopic endometrial tissue outside the uterine cavity that responds to hormonal stimulation. It occurs most commonly in pelvic sites such as the ovaries, posterior cul-de-sac, ligaments of the uterus, pelvic peritoneum and rectovaginal septum and is found in 8%–15% of all menstruating women. Extrapelvic endometriosis is less common but can affect many si...