Endometrial stromal tumor is an uncommon uterine tumor comprising <10% of all uterine mesenchymal neoplasms. The diagnosis of low-grade endometrial stromal sarcoma (LGESS) is based on characteristic histopathological features showing diffuse growth of uniform stromal cells resembling those of proliferative phase endometrium and uniformly distributed small spiral arterioles and it is not problem...

Alterations in microsatellite sequences characterize hereditary nonpolyposis colorectal cancer. This microsatellite instability is due in some kindreds to a germline mutation of the mismatch repair gene hMSH2 on chromosome 2p. Although microsatellite alterations have been reported in other hereditary nonpolyposis colorectal cancer-associated tumors including endometrial and gastric cancers, suc...

A bioassay of 1,5-naphthalenediamine for possible carcinogenicity was conducted using Fischer 344 rats and B6C3F1 mice. 1,5-Naphthalenediamine was administered in the feed, at either of two concentrations, to groups of 50 male and 50 female animals of each species. The high and low dietary concentrations utilized in the chronic bioassay were, respectively, 0.1 and 0.05 percent for rats and 0.2 ...

A variety of novel endometrial ablation technologies are now in routine use. A subset of uteri that had previously undergone these treatments will ultimately be evaluated by the pathologist. However, the full spectrum of histologic changes that may result from these treatments has received only sporadic attention. The NovaSure [Hologic Corporation, Marlborough, MA, USA] endometrial ablation sys...

Uterine tumors resembling ovarian sex cord tumors (UTROSCTs) are a rare group of stromal neoplasms containing prominent sex cord-like elements. Since they were first described in 1945 by Morehead and Bowman [1], no more than 100 such tumors have been reported [2]. In a report by Clement and Scully [3], these neoplasms were divided into 2 groups on the basis of clinical and histologic patterns. ...

Chloroethane, bromoethane and ethylene oxide represent a unique set of chemicals that induce endometrial neoplasms in the uterus of B6C3F1 mice following an inhalation route of exposure. The results of the NTP's chronic bioassays with these three compounds resulted in an unusually high incidence of uterine epithelial neoplasms in B6C3F1 mice (chloroethane 86%, bromoethane 56%) and a lower incid...

Primary gastric chorioadenocarcinoma (PGC) is a rare and rapidly invasive tumor. Choriocarcinoma is usually known to be of endometrial origin and gestational; however, it has been reported in other extragenital organs, such as the gall bladder, prostate, lung, liver, and the gastrointestinal tract. Human chorionic gonadotropin related neoplasms of the stomach are seldom discussed in the literat...

as a tumor composed of admixed benign epithelial and malignant nonepithelial components, and this tumor usually develops as a solitary lesion in the uterine corpus (1). These neoplasms can develop in the endometrial tissue as well as in the ectopic foci of endometriosis. Rare extrauterine müllerian adenosarcomas have been reported to arise in the ovary, cervix, vagina, pelvis, bladder and colon...

The increase in the incidence of endometrial neoplasms female population is associated with increased life expectancy and lifestyle adopted our daily lives. way we eat influences profile bacterial flora production substances that can work as suppressor tumors or oncogenic. Dysbiosis leads to changes intestinal vaginal barrier promotes chronic inflammation metabolic hormonal influence carcinogen...