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Galectins, an ancient lectin family, are characterized by specific binding of beta-galactosides through evolutionary conserved sequence elements of carbohydrate-recognition domain (CRD). A structurally unique member of the family is galectin-3; in addition to the CRD it contains a proline- and glycine-rich N-terminal domain (ND) through which is able to form oligomers. Galectin-3 is widely spre...

We describe the design and implementation of a nite domain constraint solver embedded in a Prolog system using an extended uniication mechanism via attributed variables as a generic constraint interface. The solver is essentially a scheduler for indexicals, i.e. reactive functional rules encoding local consistency methods performing incre-mental constraint solving or entailment checking, and gl...

An open ended list is a well known data structure in Prolog programs. It is frequently used to represent a value changing over time, while this value is referred to from several places in the data structure of the application. A weak point in this technique is that the time complexity is linear in the number of updates to the value represented by the open ended list. In this programming pearl w...

Most biological systems have some sort of adaptation to our planet’s cycle of day and night. This adaptation is a current subject of scientific research, and serves as inspiration to develop a multi-agent simulation to investigate the evolution of complexity in an open-ended evolutionary framework. In a previous work, we created a simulated world where artificial organisms evolve to synchronize...