that metastasis often occurs early in tumor progression. In early stage breast cancer, for example, a significant percentage of patients exhibit circulating tumor cells (CTC's) and disseminated bone marrow tumor cells (DTC's) [1,2]. More direct experimental evidence for " early metastasis " has been observed in studies of transgenic mice expressing a cancer-causing oncogene where the primary ca...

Five patients with constrictive pericarditis are described, in whom the main constriction was found at operation to be concentrated in an annular band forming a hoop around the pericardial sac, at the level of the atrio-ventricular grooves. In four of them, although the constriction was predominantly at this annulus, the effect on the heart was similar to that resulting from more generalized co...

Time-asymmetric state-evolution properties while encircling an exceptional point are presently of great interest in search of new principles for controlling atomic and optical systems. Here, we show that encircling-an-exceptional-point interactions that are essentially reciprocal in the linear interaction regime make a plausible nonlinear integrated optical device architecture highly nonrecipro...

The precursors of primary Rhegmatogenous retinal detachment (PRRD) are changes in the vitreous body leading to tractional forces on the retina inducing a break through which fluid gains access to the sub retinal space [1]. To achieve successful retinal reattachment, the goal of surgery for RRD is to close all retinal breaks and relieve vitreous traction, which may also reduce the incidence of n...

(A) BAND ELECTRODE ARRAY (B) CIRCUMFERENTIAL SPOT (C) LONGITUDINAL SPOT ELECTRODE ARRAY ELECTRODE ARRAY FIGUBE 1. Four terminal systems for the measurement of thoracic impedance. A. Flexible metal electrodes encircling neck and thorax. 50 kHz constant sinusoidal current (1 mA rms) was applied to electrodes 1, 4. Voltage changes reflecting thoracic impedance changes were picked up from electrode...

Core-satellite ZnS-Au nanoassemblies, in which each of the ZnS nanospheres was surrounded by a few Au nanoparticles, have been successfully prepared with a facile L-cysteine-assisted hydrothermal approach. The density of Au nanoparticles encircling each ZnS nanosphere can be readily controlled through suitably modulating the concentration of Au added. Because of the difference in band structure...