نتایج جستجو برای: empirical therapy

تعداد نتایج: 853353  

2004
Mónica Caniupán Marileo

Data warehouses (DWs) can become inconsistent when some dimensional constraints are not satisfied by the dimension instances. In this paper, we present preliminary results about the effects of the violation of partitioning constraints in homogeneous dimension instances over aggregation queries, and in particular over the summarizability property (SUMM) of the DWs. We are interested in finding w...

2014
Christian Brownlees Emilien Joly Gábor Lugosi

The purpose of this paper is to discuss empirical risk minimization when the losses are not necessarily bounded and may have a distribution with heavy tails. In such situations usual empirical averages may fail to provide reliable estimates and empirical risk minimization may provide large excess risk. However, some robust mean estimators proposed in the literature may be used to replace empiri...

2008
Guillaume Lecué Shahar Mendelson

In this note we study lower bounds on the empirical minimization algorithm. To explain the basic set up of this algorithm, let (Ω, μ) be a probability space and set X to be a random variable taking values in Ω, distributed according to μ. We are interested in the function learning (noiseless) problem, in which one observes n independent random variables X1, . . . , Xn distributed according to μ...

Journal: :The Journal of antimicrobial chemotherapy 2007
Michael D Parkins Deana M Sabuda Sameer Elsayed Kevin B Laupland

OBJECTIVES Although inadequate antimicrobial therapy has been demonstrated in multiple studies to increase the risk for death in bacterial infections, few data investigating the effect of antifungal therapy on outcome of serious fungal disease are available. We sought to assess the adequacy of empirical therapy and its effect on mortality in invasive Candida species infections. METHODS Popula...

Journal: :The Journal of antimicrobial chemotherapy 2015
Sheila López-Góngora Ignasi Puig Xavier Calvet Albert Villoria Mireia Baylina Neus Muñoz Jordi Sanchez-Delgado David Suarez Victor García-Hernando Javier P Gisbert

BACKGROUND The cure rate of standard triple therapy for Helicobacter pylori infection is unacceptably low. Susceptibility-guided therapies (SGTs) have been proposed as an alternative to standard empirical treatments. The aim of this study was to perform a systematic review and meta-analysis evaluating the efficacy of SGTs. METHODS A systematic search was performed in multiple databases. Rando...

2014
Jin Seok Kim June-Won Cheong Ho Jin Shin Jong Wook Lee Je-Hwan Lee Deok-Hwan Yang Won Sik Lee Hawk Kim Joon Seong Park Sung-Hyun Kim Yang Soo Kim Jae-Yong Kwak Yee Soo Chae Jinny Park Young Rok Do Yoo Hong Min

PURPOSE To identify prognostic factors for the outcomes of empirical antifungal therapy, we performed a multicenter, prospective, observational study in immunocompromised patients with hematological malignancies. MATERIALS AND METHODS Three hundred seventy-six patients (median age of 48) who had neutropenic fever and who received intravenous (IV) itraconazole as an empirical antifungal therap...

2015
Yong Kwan Lim Mi-Kyung Lee Tae-Hyoung Kim

Extended-spectrum beta-lactamases (ESBLs) are enzymes that confer increased resistance to commonly used antibiotics. The prevalence rates of ESBL producing bacteria are increasing, and the associated increase in morbidity and mortality is becoming a public health concern. ESBL producers are emerging as an important cause of urinary tract infection (UTI) and empirical therapy should therefore be...

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