BACKGROUND This randomized, double-blind study tested the hypothesis that, in comparison with midazolam, premedication with oral clonidine reduces the incidence of emergence agitation in preschool children anaesthetized with sevoflurane. METHODS Sixty-eight ASA I-II children undergoing circumcision were randomized into three groups to receive different oral premedication given 30 min before a...

Emergence delirium (ED) also referred to as emergence agitation (EA) is a well documented phenomenon occurring in children and adults in the immediate postoperative period. With the recent popularity of the newer inhalation agents desflurane and sevoflurane, numerous clinical studies have been published questioning the association of these anesthetics with an increased incidence of emergence de...

BACKGROUND The present study tested the effect of midazolam administration after sevoflurane anesthesia against emergence agitation in children in the recovery phase. METHODS A total of 60 children presenting for ophthalmic surgery under sevoflurane anesthesia were randomly placed in four groups from Group I to Group IV. Before the end of the surgery, we injected normal saline 2 ml in Group I...

BACKGROUND Sevoflurane can be used as a sole agent for intubation in children, but studies have suggested that it is associated with emergence agitation. Fentanyl infusions can be used both to facilitate intubation and decrease emergence agitation. We investigated the effects of fentanyl on conditions at intubation and on emergence from sevoflurane anaesthesia without confounding nitrous oxide ...

Introduction Though postoperative excitement has been a feature of general anesthesia since before the development of most of our modern inhalational anesthetics, the number of studies examining the incidence of postoperative agitation has increased exponentially since the introduction of the poorly soluble inhalation agents sevoflurane and desflurane into routine anesthesia practice. Eckenhoff...

Editor—Emergence agitation is a topic of clinical interest since the introduction of sevoflurane and desflurane, and it remains oneoftheunansweredquestionsforthepaediatricanaesthetist. The incidence is reported to be between 10% and 80% depending on definition and evaluation scale used. Emergence agitation, although self-limited, may require physical restraint and is a considerable source of di...