نتایج جستجو برای: electrolysis tim

تعداد نتایج: 12936  

Journal: :Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1999
J D Rich B P Dickinson A B Flaxman E Mylonakis

Electrolysis, a permanent hair-removal technique, involves the Molluscum contagiosum is a communicable viral disease that use of any of three different methods: galvanic electrolysis, theris confined to the skin. Molluscum contagiosum manifests itself molysis, or the blend method. In galvanic electrolysis, a needle as smooth-surfaced, firm, spherical papules with umbilication of (0.005–0.015 mm...

2014
Alfonso García-López José A Paczka Jesús Jiménez-Román Curt Hartleben

BACKGROUND Fixed-combination ocular hypotensives have multiple advantages, but triple-therapy dorzolamide/brimonidine/timolol (dorz/brim/tim) is only available in Latin and South America, and information on its relative efficacy is limited. This study compares the efficacy and tolerability of fixed-combination bimatoprost/timolol (bim/tim) and dorz/brim/tim in Mexican patients with primary open...

Journal: :The Journal of Experimental Medicine 2005
Sumone Chakravarti Catherine A. Sabatos Sheng Xiao Zsolt Illes Eugene K. Cha Raymond A. Sobel Xin X. Zheng Terry B. Strom Vijay K. Kuchroo

Identification of the T cell immunoglobulin mucin-domain containing (Tim) gene family introduced a new family of cell surface molecules that is involved in the regulation of immune responses. We previously demonstrated that Tim-3 is expressed on terminally differentiated T helper (Th)1 cells, and serves to regulate Th1 immune responses. Here, we describe the identification and function of Tim-2...

2015
Chiao-Wen Kang Avijit Dutta Li-Yuan Chang Jayashri Mahalingam Yung-Chang Lin Jy-Ming Chiang Chen-Yu Hsu Ching-Tai Huang Wan-Ting Su Yu-Yi Chu Chun-Yen Lin

TIM-3 functions to enforce CD8+ T cell exhaustion, a dysfunctional state associated with the tolerization of tumor microenvironment. Here we report apoptosis of IFN-γ competent TIM-3+ population of tumor-infiltrating CD8+ T cells in colon cancer. In humans suffering from colorectal cancer, TIM-3+ population is higher in cancer tissue-resident relative to peripheral blood CD8+ T cells. Both the ...

Journal: :Protein engineering, design & selection : PEDS 2008
Markus Alahuhta Mikko Salin Marco G Casteleijn Christian Kemmer Ibrahim El-Sayed Koen Augustyns Peter Neubauer Rik K Wierenga

A monomeric variant of triosephosphate isomerase (TIM) with a new engineered binding groove has been characterized further. In this variant (ml8bTIM), the phosphate binding loop had been shortened, causing the binding site to be much more extended. Here, it is reported that in the V233A variant of ml8bTIM (A-TIM), three important properties of the wild-type TIM active site have been restored: (...

2002
C. H. Castano A. G. Lipson S. O. Kim G. H. Miley

A sensitive open-type calorimeter was used to measure excess heat production during electrolysis in Li2SO4/H2O solution with Pt-anode and Pd-Ni thin film cathodes 9000 Å thick, sputtered on Al2O3 substrate. In order to estimate the actual performance and possible measurement errors during electrolysis in the calorimeter used, including heat convection, bubbling and possible H2+O2 recombination,...

Journal: :The Journal of Experimental Medicine 2007
Sheng Xiao Nader Najafian Jay Reddy Monica Albin Chen Zhu Eric Jensen Jaime Imitola Thomas Korn Ana C. Anderson Zheng Zhang Cristina Gutierrez Thomas Moll Raymond A. Sobel Dale T. Umetsu Hideo Yagita Hisaya Akiba Terry Strom Mohamed H. Sayegh Rosemarie H. DeKruyff Samia J. Khoury Vijay K. Kuchroo

It has been suggested that T cell immunoglobulin mucin (Tim)-1 expressed on T cells serves to positively costimulate T cell responses. However, crosslinking of Tim-1 by its ligand Tim-4 resulted in either activation or inhibition of T cell responses, thus raising the issue of whether Tim-1 can have a dual function as a costimulator. To resolve this issue, we tested a series of monoclonal antibo...

Journal: :The EMBO journal 1999
V Suri A Lanjuin M Rosbash

The timeless protein (TIM) is a central component of the circadian pacemaker machinery of the fruitfly Drosophila melanogaster. Both TIM and its partner protein, the period protein PER, show robust circadian oscillations in mRNA and protein levels. Yet the role of TIM in the rhythm generation mechanism is largely unknown. To analyze TIM function, we constructed transgenic flies that carry a hea...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2014
Minghua Li Sherimay D Ablan Chunhui Miao Yi-Min Zheng Matthew S Fuller Paul D Rennert Wendy Maury Marc C Johnson Eric O Freed Shan-Lu Liu

Accumulating evidence indicates that T-cell immunoglobulin (Ig) and mucin domain (TIM) proteins play critical roles in viral infections. Herein, we report that the TIM-family proteins strongly inhibit HIV-1 release, resulting in diminished viral production and replication. Expression of TIM-1 causes HIV-1 Gag and mature viral particles to accumulate on the plasma membrane. Mutation of the phosp...

2013
Hyun-Bae Jie Jing Li Raghvendra Srivastava Robert L Ferris

Although T-cell immunoglobulin mucin 3 (TIM-3) does not contain inhibitory or death signaling motifs in its cytoplasmic domain, it has been proposed to be associated with T cell suppression and/or exhaustion. However, several lines of evidence suggest that TIM-3 can stimulate T cells as a costimulatory molecule by coupling Src family tyrosine kinase Fyn and the p85 phosphatidylinositol 3-kinase...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید