نتایج جستجو برای: electrochemotherapy intraoperative

تعداد نتایج: 30086  

2015
Ales Groselj Bor Kos Maja Cemazar Jure Urbancic Grega Kragelj Masa Bosnjak Biserka Veberic Primoz Strojan Damijan Miklavcic Gregor Sersa

BACKGROUND Electrochemotherapy provides highly effective local treatment for a variety of tumors. In deep-seated tumors of the head and neck, due to complex anatomy of the region or inability to cover the whole tumor with standard electrodes, the use of long single needle electrodes is mandatory. In such cases, a treatment plan provides the information on the optimal configuration of the electr...

Journal: :acta medica iranica 0
mohammad moazeni bitgani department of surgery, school of medicine, shahrekord university of medical sciences, shahrekord, iran. hossein madineh department of anesthesiology, school of medicine, shahrekord university of medical sciences, shahrekord, iran.

endotracheal tube (ett) cuff herniation is a rare, and often difficult to diagnose, cause of bronchial obstruction. we present a case of outside cuff herniation of an endotracheal tube that caused pulmonary right lung atelectasis. a 29-year-old man ,a case of car accident with multiple fractures, was admitted to the emergency ward and transferred to the operating room(or) for open reduction and...

Ameneh Sazgarnia, Fatemeh Homaei Habibollah Esmaily Majid Valizadeh Mohammad Hossein Bahreyni-Toosi

Objective(s) This study was carried out in order to evaluate the effects of electrochemotherapy, electrical pulses and chemotherapeutic drugs on the killing of cancerous cells and their probable synergistic effects. Materials and Methods Electrochemotherapy treatments conducted on MCF-7 cell line derived from human breast adenocarcinoma tumor using four chemotherapeutic drugs including bleom...

Journal: :Current Oncology 2009

2003
Anita Gothelf Lluis M. Mir

Introduction Electroporation is characteristed by the use of short, high voltage pulses which transiently permeabilize the cell membrane. As electroporation can be used to introduce various molecules directly into the cell cytosol, an obvious use has been to introduce chemotherapeutic drugs directly into cancer cells (electrochemotherapy). Many chemotherapeutic drugs are lipophilic and enter ce...

2013
Louise Wichmann Matthiessen Helle Hjorth Johannesen Kristin Skougaard Julie Gehl Helle Westergren Hendel

BACKGROUND Electrochemotherapy is a local anticancer treatment very efficient for treatment of small cutaneous metastases. The method is now being investigated for large cutaneous recurrences of breast cancer that are often confluent masses of malignant tumour with various degrees of inflammation. To this end 18-Flourine-Flourodeoxyglucose-Positron Emission Tomography/Computed Tomography (FDG-P...

2016
Simona Kranjc Matej Kranjc Janez Scancar Jure Jelenc Gregor Sersa Damijan Miklavcic

INTRODUCTION Pulsed electromagnetic field (PEMF) induces pulsed electric field, which presumably increases membrane permeabilization of the exposed cells, similar to the conventional electroporation. Thus, contactless PEMF could represent a promising approach for drug delivery. MATERIALS AND METHODS Noninvasive electroporation was performed by magnetic field pulse generator connected to an ap...

Journal: :Technology in cancer research & treatment 2011
I Edhemovic E M Gadzijev E Brecelj D Miklavcic B Kos A Zupanic B Mali T Jarm D Pavliha M Marcan G Gasljevic V Gorjup M Music T Pecnik Vavpotic M Cemazar M Snoj G Sersa

Electrochemotherapy is now in development for treatment of deep-seated tumors, like in bones and internal organs, such as liver. The technology is available with a newly developed electric pulse generator and long needle electrodes; however the procedures for the treatment are not standardized yet. In order to describe the treatment procedure, including treatment planning, within the ongoing cl...

Journal: :BioMedical Engineering OnLine 2009
Selma Corovic Janez Bester Damijan Miklavcic

BACKGROUND Electrochemotherapy is an effective approach in local tumour treatment employing locally applied high-voltage electric pulses in combination with chemotherapeutic drugs. In planning and performing electrochemotherapy a multidisciplinary expertise is required and collaboration, knowledge and experience exchange among the experts from different scientific fields such as medicine, biolo...

Journal: :In vivo 2008
Enrico P Spugnini Ivan Dotsinsky Nikolay Mudrov Massimiliano Bufalini Giovanni Giannini Gennaro Citro Florinda Feroce Alfonso Baldi

Canine anal sac gland carcinoma (ASGC) is a frequently described neoplasm that is highly aggressive and can frequently lead to metastatic spread. In this paper, we describe the successful treatment of an incompletely excised ASGC by using cisplatin selectively driven within the tumor cells by trains of biphasic pulses. The dog received two courses of electrochemotherapy 14 days apart. Neither s...

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