نتایج جستجو برای: eicosapentaenoic acid epa
تعداد نتایج: 752719 فیلتر نتایج به سال:
Fatty acid composition has an important role in cellular structure and function. Inflammatory behavior of the airway epithelial cells can be changed due to the manipulation of their fatty acid content, which has a critical importance in asthma. The objective of the present study was to determine the fatty acid composition of human airway epithelial cells after co-culturing with eicosapentaenoic...
Treatment with the omega-3 polyunsaturated fatty acids (PUFAs) docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) exerts cardioprotective effects, and suppresses Ca2+-induced opening of the mitochondrial permeability transition pore (MPTP). These effects are associated with increased DHA and EPA, and lower arachidonic acid (ARA) in cardiac phospholipids. While clinical studies suggest t...
The effect of a flaxseed oil-based diet on tumor necrosis factor a (TNFa) and interleukin lj3 (IL-I f3) synthesis was examined in healthy volunteers. Use of flaxseed oil in domestic food preparation for 4 wk inhibited TNFa and IL-l production by ‘30%. Fish-oil supplementation (9 g/d) continued for a further 4 wk; TNFa and IL-l synthesis were inhibited by 74% and 80%, respectively. There was a s...
the objective of the present study was to determine chemical composition and fatty acid profile of common kilka ,clupeonella cultriventris caspia, in the caspian sea. the chemical analysis revealed that the protein and lipid content of common kilka were 15.05 and 6.5% of the fresh weight, and total mufa, pufa and sfa were found to be 37.00, 32.89 and 29.03% respectively. palmitic acid (16:0) am...
Non-alcoholic fatty liver disease (NAFLD), the hepatic manifestation of obesity, is an emerging risk factor for hepatocellular carcinoma (HCC). Accumulating evidence has shown that chronic inflammation represents a plausible link between obesity and HCC and that the pro-inflammatory cytokine interleukin (IL)-6 contributes to the development of obesity-related HCC. In the present study, we aimed...
In the present intervention study we compared the effects of alpha-linolenic acid with those of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on platelet aggregation in vitro and ex vivo in healthy non-institutionalized elderly subjects. We also compared the effects of alpha-linolenic acid on platelet aggregation in elderly subjects with those in younger volunteers. During a run-in...
Human skin fibroblasts can convert arachidonic acid to 14- and 16-carbon polyunsaturated fatty acid products by peroxisomal beta-oxidation. The purpose of this study was to determine whether similar products are formed from eicosapentaenoic acid (EPA) and whether EPA and arachidonic acid compete for utilization by this oxidative pathway. Three radiolabeled metabolites with shorter retention tim...
AIM The Japan EPA Lipid Intervention Study (JELIS) reported a 19% reduction of the risk for coronary artery disease after long-term use of pure eicosapentaenoic acid (EPA) in Japanese patients with hypercholesterolemia. The variation in plasma fatty acid composition influenced the risk of coronary events. The aim of this study was to examine in JELIS participants the possible correlation of cha...
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