We tested the generally accepted concept that increased gluconeogenesis (GNG) and endogenous glucose production (EGP) are the main reasons for postabsorptive hyperglycemia in patients with type 2 diabetes mellitus (T2DM). GNG was measured with the (2)H(2)O method by use of both the C5-to-C2 ratio (C5/C2, with gas chromatography-mass spectrometry) and the C5-to-(2)H(2)O ratio (C5/(2)H(2)O, with ...

OBJECTIVE To determine the contribution of hepatic insulin resistance to the pathogenesis of impaired fasting glucose (IFG). RESEARCH DESIGN AND METHODS Endogenous glucose production (EGP) and glucose disposal were measured in 31 subjects with IFG and 28 subjects with normal fasting glucose (NFG) after an overnight fast and during a clamp when endogenous secretion was inhibited with somatosta...

The explosive growth in the variety and size of social networks has focused attention on searching these networks for useful structures. Like the internet or the telephone network, the ability to efficiently search large social networks will play an important role in the extent of their use by individuals and organizations alike. However, unlike these domains, search on social networks is likel...

This study illuminates the genre-based pedagogy delivered by a novice EAP teacher for teaching discussion section writing to cross-discipline undergraduates in China. Followed demonstration of specifics genre teaching, researcher tapped into effectiveness through an examination student-produced submissions. Autoethnography and qualitative research methods were used analyze video-recording, jour...

OBJECTIVE 1) To evaluate the effect of a single oral dose of hexyl-insulin monoconjugate 2 (HIM2) on the rate of whole-body glucose disposal (Rd) and endogenous glucose production (EGP) in healthy nondiabetic subjects, 2) to examine the reproducibility of HIM2 on glucose metabolism, and 3) to compare the results obtained with HIM2 with those using a bioequivalent dose of subcutaneous lispro ins...

When making use of inter-domain routing in a MANET environment, certain interactions are required between the Exterior Gateway Protocol (EGP) and the Interior Gateway Protocol (IGP, such as OLSR or AODV). Unlike the norm in conventional fixed networks, many MANET protocols assume that every node in a network is a router, and as such a different mechanism to traditional dual-IGP/EGP functionalit...

We have separated the effect of insulin on glucose distribution/transport, glucose disposal, and endogenous production (EGP) during an intravenous glucose tolerance test (IVGTT) by use of a dual-tracer dilution methodology. Six healthy lean male subjects (age 33 +/- 3 yr, body mass index 22.7 +/- 0.6 kg/m(2)) underwent a 4-h IVGTT (0.3 g/kg glucose enriched with 3-6% D-[U-(13)C]glucose and 5-10...

OBJECTIVE To assess the role of adiposity on the pharmacodynamics of basal insulins NPH, detemir, and glargine in type 2 diabetes mellitus (T2DM), as estimated by glucose infusion rate (GIR) and endogenous glucose production (EGP) rate in the euglycemic clamp. RESEARCH DESIGN AND METHODS We examined the variables that best predicted GIR and EGP in 32-h clamp studies after treatment with subcu...