Supernumerary centrosomes contribute to spindle defects and aneuploidy at mitosis, but the effects of excess centrosomes during interphase are poorly understood. In this paper, we show that interphase endothelial cells with even one extra centrosome exhibit a cascade of defects, resulting in disrupted cell migration and abnormal blood vessel sprouting. Endothelial cells with supernumerary centr...

introduction: the formalin test is the most accepted chemical test for evaluation of nociception. it requires the injection of an adequate amount of formalin into the surface of the hindpaw. formalin test consists of phase 1 (0-7 min) and phase 2 (15-60) in which the animal shows painful behaviors. these phases are separated with a quiet phase named interphase, in which the nociceptive response...

The interphase transfer of turbulent kinetic energy TKE is an important term that affects the evolution of TKE in fluid and particle phases in particle-laden turbulent flow. This work shows that the interphase TKE transfer terms must obey a mathematical constraint, which in the limiting case of statistically homogeneous flow with zero mean velocity in both phases, requires these terms be equal ...

The tensile properties of multiscale, hybrid, thermoplastic-based nanocomposites reinforced with nano-CaCO3 particles and micro–short glass fibers (SGF) were predicted by a two-step, three-dimensionalmodel using ANSYS finite element (FE) software. Cylindrical and cuboid representative volume elements were generated to obtain the effective behavior of the multiscale hybrid composites. In the fir...

Introduction I. 3D organization of the chromatin in the interphase nucleus 1. Relationship of the chromatin with the nucleus structures 2. Notion of chromosomal territories 3. Topography of the territories 4. Interface between neighbor territories 5. Organization model of the chromatin in the interphase nucleus II. Relative evolution of the territories when compared to each other during the suc...

Introduction: The formalin test is the most accepted chemical test for evaluation of nociception. It requires the injection of an adequate amount of formalin into the surface of the hindpaw. Formalin test consists of phase 1 (0-7 min) and phase 2 (15-60) in which the animal shows painful behaviors. These phases are separated with a quiet phase named interphase, in which the nociceptive respon...

A MODEL FOR CHROMOSOME BEHAVIOR DURING MITOSIS AND MEIOSIS .................................... .. The Mitotic Cell Cycle .....................................................................•............................................ Interphase ........................................................................................................................................ . Metaphase ...

within the effective-field theory with correlations (eft), a transverse random field spin-1 ising model on the simple cubic (z=6) lattice is studied. the phase diagrams, the behavior of critical points, transverse magnetization,  internal energy, magnetic specific heat are obtained numerically and discussed for different values of p the concentration of the random transverse field.