نتایج جستجو برای: edl
تعداد نتایج: 1154 فیلتر نتایج به سال:
Dynamic epistemic logic (DEL) as viewed by Baltag et col. and propositional dynamic logic (PDL) offer different semantics of events. On the one hand, DEL adds dynamics to epistemic logic by introducing so-called epistemic action models as syntactic objects into the language. On the other hand, PDL has instead transition relations between possible worlds. This last approach allows to easily intr...
AIM To investigate the hypothesis that mitochondrial efficiency (i.e. P/O ratio) is higher in type I than in type II fibres during submaximal rates of respiration. METHODS Mitochondria were isolated from rat soleus and extensor digitorum longus (EDL) muscles, representing type I and type II fibres, respectively. Mitochondrial efficiency (P/O ratio) was determined with pyruvate (Pyr) or palmit...
The sarcoplasmic reticulum (SR) and transverse tubular system (TTS) of a fast-twitch muscle (extensor digitorum longus-EDL) and a slow-twitch muscle (soleus-SOL) of the mouse were examined during postnatal development. Muscles of animals newborn to 60 days old were fixed in glutaraldehyde and osmium tetroxide and examined with an electron microscope. At birth the few T tubules were often orient...
Germinario, E., A. Esposito, A. Megighian, M. Midrio, R. Betto, and D. Danieli-Betto. Effects of modulators of sarcoplasmic Ca release on the development of skeletal muscle fatigue. J Appl Physiol 96: 645–649, 2004; 10.1152/japplphysiol.00481.2003.—The reduced release of Ca from sarcoplasmic reticulum (SR) is considered a major determinant of muscle fatigue. In the present study, we investigate...
Myostatin is a negative regulator of muscle mass. The impact of myostatin deficiency on the contractile properties of healthy muscles has not been determined. We hypothesized that myostatin deficiency would increase the maximum tetanic force (P(o)), but decrease the specific P(o) (sP(o)) of muscles and increase the susceptibility to contraction-induced injury. The in vitro contractile propertie...
The reduced release of Ca2+ from sarcoplasmic reticulum (SR) is considered a major determinant of muscle fatigue. In the present study, we investigated whether the presence of dantrolene, an established inhibitor of SR Ca2+ release, or caffeine, a drug facilitating SR Ca2+ release, modifies muscle fatigue development. Accordingly, the effects of Ca2+ release modulators were analyzed in vitro in...
The effect of microgravity on skeletal muscles has so far been examined in rat and mice only after short-term (5-20 day) spaceflights. The mice drawer system (MDS) program, sponsored by Italian Space Agency, for the first time aimed to investigate the consequences of long-term (91 days) exposure to microgravity in mice within the International Space Station. Muscle atrophy was present indistinc...
The effect of dietary fat content on phospholipid fatty acid profile is muscle fiber type dependent.
A high-saturated-fat diet (HFD) induces obesity and insulin resistance (IR). IR has been linked to alterations and increased saturation in the phospholipid composition of skeletal muscles. We aimed to determine whether HFD feeding affects fatty acid (FA) membrane profile in a muscle fiber type-specific manner. We measured phospholipid FAs and expression of FA synthesis genes in oxidative soleus...
In this work, the effects of electrical double layer (EDL) near the solid/ liquid interface, on three dimensional heat transfer characteristic and pressure drop of water flow through a rectangular microchannel numerically are investigated. An additional body force originating from the existence of EDL is considered to modify the conventional Navier-stokes and energy equations. These modified eq...
1. Rat soleus (SOL) and extensor digitorum longus (EDL) muscles, stored for 2-6hrs at 30•Ž in Krebs' solution with rat serum in higher concentration than 2%, showed low internal Na and high internal K concentrations as compared with control muscles stored in the normal saline solution. Such a serum effect on the EDL muscles decreased with lowering of temperature of the external solution. 2. The...
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