نتایج جستجو برای: eccrine sweat gland carcinoma
تعداد نتایج: 464794 فیلتر نتایج به سال:
Ductal eccrine carcinoma (DEC) is a rare sweat gland carcinoma with ductular differentiation. Clinically, it is characterized by a slowly growing, hardened plaque or nodule predominantly located on the head and neck. Histologically, DEC shares similar features to invasive breast carcinoma, thus causing great diagnostic challenges. We report a 69-year-old woman who presented with a hardened plaq...
ALK-positive primary systemic anaplastic large cell lymphoma with extensive cutaneous manifestation.
localization of keratins and involucdn in solar keratosis and Bowen's disease. Am J Dermatopathol 1995; 17: 151-157. 4. Mai K.T. Alhalouly T. Landry D, Stinson WA. Perkins DG, Yazdi HM. Pagetoid variant of actinic keratosis with or with -out squamous cell carcinoma of sun-exposed skin: a lesion simulating extramammary Paget's disease. Histopathology 2002; 41:331-336. 5. Ansai S. Mihara I. Sebac...
Long tubular excretory duct of the human eccrine sweat gland has been divided by light microscopy into three portions: the initial or coiled portion which is included in the glandular coil, the ascending or straight portion which runs in the dermis toward the epidermis and the terminal or intraepidermal portion which ascends spirally through the epidermis toward the free surface of the skin to ...
Eccrine sweat glands are essential for sweating and thermoregulation in humans. Loss-of-function mutations in the Ca2+ release-activated Ca2+ (CRAC) channel genes ORAI1 and STIM1 abolish store-operated Ca2+ entry (SOCE), and patients with these CRAC channel mutations suffer from anhidrosis and hyperthermia at high ambient temperatures. Here we have shown that CRAC channel-deficient patients and...
Serine proteases can induce cell signaling by stimulating G-protein-coupled receptors, called proteinase-activated receptors (PAR's) on a variety of epithelial cells. While PAR-2, one such receptor, activates cell signaling in a secretory cell line derived from human sweat glands, there was no information on their presence and effects on intact sweat glands. PAR-2 presence and activation of ecc...
BACKGROUND Eccrine porocarcinoma (EPC), a slow-growing carcinoma of the sweat gland, is a rare condition documented only in a small number of case series. Due to its rarity, guidelines and specific recommendations are not widely available. Accordingly, many dermatologists encounter difficulty in diagnosing and treating EPC. The aim of this study is to report the clinical and pathological featur...
Abnormal ductal NaCl absorption has been known as the only defect in cystic fibrosis (CF) sweat glands. We have fortuitously found that the secretory portion of CF sweat glands is also abnormal in that it failed to show a sweating response to beta adrenergic stimulation (isoproterenol, [ISO]) both in vivo and in vitro. For the in vitro sweat test, eccrine sweat glands were isolated from skin bi...
INTRODUCTION Eccrine porocarcinoma is an uncommon malignant adnexal tumor of the skin. Eccrine porocarcinoma is an adenocarcinoma of the eccrine sweat gland with a propensity to recur locally and gives metastases to regional lymph nodes. This paper presents a cytologic diagnosis by fine needle aspiration of an eccrine porocarcinoma along with histopathology and immunocyto-histochemistry. CASE...
Introduction: Microcystic adnexal tumor is a rare sclerosing variant of ductal carcinoma of eccrine sweat gland which is deeply invasive. This tumor which is said to have high recurrence rate is often misdiagnosed as other benign or malignant skin lesions and improper treatment is administered. Case Report: We report herein a 59-year-old man who underwent incisional biopsy for a congenital ...
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