نتایج جستجو برای: eccrine glands
تعداد نتایج: 39859 فیلتر نتایج به سال:
Eccrine porocarcinoma is a rare neoplasm that originates from the intraepidermal ductal portion of the eccrine sweat gland, and it usually occurs on the pre-existing lesion of benign eccine poroma. Its occurrence is more common in females and elderly persons. We present a case of a 44-year-old man who suffered from eccrine porocarcinoma, which developed on the right scrotum and pelvic area with...
BACKGROUND Protease-activated receptor 2 (PAR-2) participates in various biological activities, including the regulation of epidermal barrier homeostasis, inflammation, pain perception, and melanosome transfer in the skin. OBJECTIVE To evaluate the basic physiological role of PAR-2 in skin. METHODS We investigated PAR-2 expression in human epidermis, skin tumors, and cultured epidermal cell...
Nodular hidradenoma is a rare benign tumour of eccrine sweat gland. It usually presents as a solitary, intradermal nodule 0.5 -2 cms in diameter in most instances. It may be red, brown or bluish and sometimes may show superficial ulceration. We are presenting a case report of 50 years old female who presented with painless swelling measuring 3×3 cms over right leg for 2 years. Excisional biopsy...
Sweating is a normal and important mechanism of thermoregulation which is essential for survival. When sweating becomes excessive, the resulting condition is called hyperhidrosis. While hyperhidrosis is not a fatal condition, it can greatly affect one’s quality of life due to its psychological and social impact. To understand this condition, it is necessary to explore the biology of sweat gland...
Nodular hidradenoma (HA) otherwise called as solid cystic HA/ Eccrine acrospiroma originate from distal excretory duct of sweat gland [1]. Origin from apocrine gland of breast has been seldom noted. It’s slow growing benign freely mobile solitary tumor with solid cystic consistency. Scalp, face and extremities are common locations. The usual age of presentation is 20-50 years showing female pre...
An adaptive variant of the human Ectodysplasin receptor, EDARV370A, is one of the strongest candidates of recent positive selection from genome-wide scans. We have modeled EDAR370A in mice and characterized its phenotype and evolutionary origins in humans. Our computational analysis suggests the allele arose in central China approximately 30,000 years ago. Although EDAR370A has been associated ...
A 71-year-old woman was referred to our clinic with a 2-month history of pain and exudate from her right first toe. Physical examination revealed subungual nodule that elevated the nail plate produced distal onycholysis. We performed onychectomy removed nodule. histopathological specimen showed hyperkeratosis acanthosis in epidermis, papillomatosis dilated vessels superficial dermis, aggregatio...
Syringomas are benign adnexal tumors derived from the intraepidermal portion of eccrine glands. They mostly found in young to middle aged women as asymptomatic (sometimes pruritic), soft, and yellowish-brown or skin-colored papules with bilaterally symmetrical distribution. The lesions have a predilection for periorbital area (primarily lower eyelids) cheeks. A variant-eruptive syringoma presen...
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