let $g=(v,e)$ be a connected graph. the eccentric connectivity index of $g$, $xi^{c}(g)$, is defined as $xi^{c}(g)=sum_{vin v(g)}deg(v)ec(v)$, where $deg(v)$ is the degree of a vertex $v$ and $ec(v)$ is its eccentricity. the eccentric distance sum of $g$ is defined as $xi^{d}(g)=sum_{vin v(g)}ec(v)d(v)$, where $d(v)=sum_{uin v(g)}d_{g}(u,v)$ and $d_{g}(u,v)$ is the distance between $u$ and $v$ ...

QUESTION Is an injury prevention program consisting of 10 exercises designed to improve stability, muscle strength, co-ordination, and flexibility of the trunk, hip and leg muscles (known as The11) cost effective in adult male amateur soccer players? DESIGN Cost-effectiveness analysis of a cluster-randomised controlled trial. PARTICIPANTS 479 adult male amateur soccer players aged 18-40 yea...

Exercise-induced muscle injury in humans frequently occurs after unaccustomed exercise, particularly if the exercise involves a large amount of eccentric (muscle lengthening) contractions. Direct measures of exercise-induced muscle damage include cellular and subcellular disturbances, particularly Z-line streaming. Several indirectly assessed markers of muscle damage after exercise include incr...

Eccentric connectivity index has been found to have a low degeneracy and hence a significant potential of predicting biological activity of certain classes of chemical compounds. We present here explicit formulas for eccentric connectivity index of various families of graphs. We also show that the eccentric connectivity index grows at most polynomially with the number of vertices and determine ...

Unaccustomed eccentric exercise is a well-documented cause of exercise-induced muscle damage. However, in trained subjects muscle injury involves only light or moderate tissue damage. Since trained rats are widely used as a model for skeletal muscle injury, here we propose a semiquantitative scoring tool to evaluate muscle damage in trained rats. Twenty male Sprague-Dawley rats were trained for...

BACKGROUND Long-term endurance sport practice leads to eccentric left ventricular hypertrophy (LVH). We aimed to compare the new 4-tiered classification (4TC) for LVH with the established 2-tiered classification (2TC) in a cohort of normotensive non-elite endurance athletes. METHODS Male participants of a 10-mile race were recruited and included when blood pressure (BP) was normal (<140/90 mm...

Background Coronary thrombosis is a dynamic process dependent on the pathological substrate, the local shear forces, and blood factors. Methods and Results We investigated the effect of a severe (80%) eccentric stenosis on fibrin(ogen) interaction with a deeply damaged vessel wall, its relation to platelet deposition in thrombus formation, and the influence of time on thrombus growth. Porcine '...

Recent increases in the discovery of high multiplicity Sub-Jovian planetary systems, in addition to discoveries of giant planets of high eccentricities in these multiple body systems, lead to questions into their origins and evolution. The study of secular interactions is not new, however it has only recently been applied to exoplanetary systems. These systems sometimes fall far from the classi...

There is little consensus on how to optimally reconstruct the posterior cruciate ligament (PCL) and the natural history of injured PCL is also unclear. The graft material (autograft vs. allograft), the type of tibial fixation (tibial inlay vs. transtibial tunnel), the femoral tunnel position within the femoral footprint (isometric, central, or eccentric), and the number of bundles in the recons...