نتایج جستجو برای: early ovarian ageing

تعداد نتایج: 785107  

Journal: :Cancer prevention research 2011
Steven J Skates Phuong Mai Nora K Horick Marion Piedmonte Charles W Drescher Claudine Isaacs Deborah K Armstrong Saundra S Buys Gustavo C Rodriguez Ira R Horowitz Andrew Berchuck Mary B Daly Susan Domchek David E Cohn Linda Van Le John O Schorge William Newland Susan A Davidson Mack Barnes Wendy Brewster Masoud Azodi Stacy Nerenstone Noah D Kauff Carol J Fabian Patrick M Sluss Susan G Nayfield Carol H Kasten Dianne M Finkelstein Mark H Greene Karen Lu

Previous screening trials for early detection of ovarian cancer in postmenopausal women have used the standard CA125 cut-point of 35 U/mL, the 98th percentile in this population yielding a 2% false positive rate, whereas the same cut-point in trials of premenopausal women results in substantially higher false positive rates. We investigated demographic and clinical factors predicting CA125 dist...

2013
SA Eshkoor P Ismail SA Rahman S Moin MY Adon

The ageing process is influenced by many internal and external factors. The toxic substances in the environment can cause genomic damages to cells, which increase the risk of early ageing. Furthermore, the cytochrome P450 1A2 (CYP1A2) gene polymorphism is a susceptibility factor and may enhance the risk of DNA damage in cells. The current study was carried out to show whether occupational expos...

2010
Nicanor I. Barrena Medel Jason D. Wright Thomas J. Herzog

Epithelial ovarian cancer remains a major women's health problem due to its high lethality. Despite great efforts to develop effective prevention and early detection strategies, most patients are still diagnosed at advanced stages of disease. This pattern of late presentation has resulted in significant challenges in terms of designing effective therapies to achieve long-term cure. One potentia...

Journal: :Current Alzheimer research 2014
Sarah J Wakefield William J McGeown Michael F Shanks Annalena Venneri

To diagnose Alzheimer's disease (AD) early, tests sensitive to neuropathology and insensitive to normal ageing are of greatest benefit. We used several neuropsychological tests to identify those best suited to distinguishing Mild Cognitive Impairment (MCI) and early AD from normal ageing. Impairments in long-term memory were found in older adults and these were even greater in MCI and AD. Older...

Journal: :middle east journal of cancer 0
syed hammad tirmazy the cancer centre, university hospitals of birmingham, birmingham, united kingdom rajanee bhana university hospital of north staffordshire, stoke on trent, united kingdom

paraneoplastic cerebellar degeneration is a rare, fatal neuronal syndrome associated with ovarian, breast and lung cancers. anti-yo antibody mediated paraneoplastic cerebellar degeneration is known to be associated with gynecological malignancies, especially ovarian cancer. however, there are no reports of anti-yo antibody associated predominant peripheral mixed sensory and motor neuropathy in ...

Journal: :international journal of reproductive biomedicine 0
tahere ashrafganjooei iraj harirchi giti iravanlo

background: tubo-ovarian abscess as a serious complication of pelvic inflammatory disease is very uncommon in sexually inactive girls. case: we report a case of tubo-ovarian abscess in a 24-year-old sexually inactive girl with transverse vaginal septum who was presented with abdominal pain and a pelvic mass and without prior surgical history and no evidences of appendicitis, inflammatory bowel ...

Journal: :Human reproduction 2007
Wouter J K Hehenkamp Nicole A Volkers Frank J M Broekmans Frank H de Jong Axel P N Themmen Erwin Birnie Jim A Reekers Willem M Ankum

BACKGROUND Ovarian failure as a complication of uterine artery embolization (UAE) for symptomatic uterine fibroids has raised concerns about this new treatment modality. METHODS We investigated the occurrence of ovarian reserve reduction in a randomized trial comparing UAE and hysterectomy by measuring follicle stimulating hormone (FSH) and anti-Mullerian hormone (AMH). A total of 177 pre-men...

2015
Katherine E Campbell Cassandra E. Szoeke Lorraine Dennerstein

As the Australian population ages, significantly more women are entering the postmenopausal stage of the climacteric, yet research focusing on the prevalence of depressive symptoms in this stage of ovarian ageing is scarce. This review will examine the information provided by studies that have a cohort with data of adequate duration to explore depressive symptom prevalence in the early and late...

Background & Aim: Ovarian cancer is the most lethal among female malignancies. So far, treatment improvements have affected patient survival, but it is still more important to provide an early diagnosis that can detect the disease in its early stages. Therefore, introducing a rapid, accurate, and low-cost method to disease detection can be important and necessary. Methods: This study introduce...

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