نتایج جستجو برای: e1e2 glycoprotein

تعداد نتایج: 90739  

Journal: :Journal of animal science 1980
M Koger

The basic objectives and procedures for successful crossbreeding of beef cattle were considered, with special reference to the levels of realized hybrid vigor that might be anticipated for different crossbreeding programs involving the American Brahman (Z1) and European (Ej) breeds. Intralocus heterozygosis levels with respect to breed origin of genes (breed heterozygosis) were computed for var...

Objective(s): Chemoresistance remains the main causes of treatment failure and mortality in cancer patients. There is an urgent need to investigate novel approaches to improve current therapeutic modalities and increase cancer patients' survival. Induction of drug efflux due to overexpression of                  P-glycoproteins is considered as an important leading cause of multidrug resistance...

Journal: :acta medica iranica 0
shabnam yazdian department of toxicology & pharmacology, faculty of pharmacy, tehran university of medical sciences, tehran, iran. najmeh fahham department of pharmacology, iran pasteur institute, tehran, iran. mohammad hossein ghahremani department of toxicology & pharmacology, faculty of pharmacy, tehran university of medical sciences, tehran, iran. monireh afzali virtual school, tehran university of medical sciences, tehran, iran. narges farsandaj department of toxicology & pharmacology, faculty of pharmacy, tehran university of medical sciences, tehran, iran. melody vatankhah department of biology, college of science, university of tehran, tehran, iran.

there is a great concern about the effect of propoxur, as one of the more common n-methyl carbamate pesticides, on human health due to its extensive use in agricultural and non-agricultural applications. caco-2 cells became resistant to propoxur, and the resistance was confirmed through mtt assay. then the cell membrane integrity and p-glycoprotein expression were measured by ldh assay and west...

Journal: :iranian journal of basic medical sciences 0
mehran mesgari abbasi drug applied research center, tabriz university of medical sciences, tabriz, iran students research committee, tabriz university of medical sciences, tabriz, iran hadi valizadeh drug applied research center, tabriz university of medical sciences, tabriz, iran hamed hamishekar drug applied research center, tabriz university of medical sciences, tabriz, iran leila mohammadnejad immunology research center, tabriz university of medical sciences, tabriz, iran parvin zakeri-milani liver and gastrointestinal diseases research center and faculty of pharmacy, tabriz university of medical sciences, tabriz, iran

objective(s):transporters have an important role in pharmacokinetics of drugs. inhibition or induction of drug transporters activity can affect drug absorption, safety, and efficacy. p-glycoprotein (p-gp) is the most important membrane transporter that is responsible for active efflux of drugs. it is important to understand which drugs are substrates, inhibitors, or inducers of p-gp to minimize...

Journal: :iranian journal of microbiology 0
n hosseini jazani center for food sciences and nutrition, urmia university of medical sciences, urmia, iran. m karimzad department of microbiology, immunology and genetics, faculty of medicine, urmia university of medical sciences, urmia, iran. s shahabi center for cellular and molecular research, urmia university of medical sciences, urmia, iran.

background and objectives: glycoprotein 96 is the primary chaperone of the endoplasmic reticulum. immunization with it induced potent cytotoxic t lymphocyte responses to intracellular bacteria. s. typhimurium is a facultative intracellular bacterium and acquired resistance against this bacterium mainly depends on activity of cytotoxic t cells. this study aimed to evaluate the capacity of glycop...

2017
Alexander Burstein Walter Stromquist

Four of these classes were separately shown previously to be enumerated by this sequence, while the five others are new. In chronological order of publication, see [1, Lemma 10] for T2, [4, Example 6.4] for T9, [9, Theorems 3.4 and 3.5] for T4, and [3, Section 3.3] for T8. The same sequence also enumerates unimodal inversion sequences [8]. An inversion sequence (subexcedant sequence, a reversal...

Journal: :Journal of virology 2015
Pierre Falson Birke Bartosch Khaled Alsaleh Birke Andrea Tews Antoine Loquet Yann Ciczora Laura Riva Cédric Montigny Claire Montpellier Gilles Duverlie Eve-Isabelle Pécheur Marc le Maire François-Loïc Cosset Jean Dubuisson François Penin

UNLABELLED In hepatitis C virus (HCV)-infected cells, the envelope glycoproteins E1 and E2 assemble as a heterodimer. To investigate potential changes in the oligomerization of virion-associated envelope proteins, we performed SDS-PAGE under reducing conditions but without thermal denaturation. This revealed the presence of SDS-resistant trimers of E1 in the context of cell-cultured HCV (HCVcc)...

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