Diabetic dyslipidemia is characterized by elevated fasting and postprandial triglycerides, low HDL-cholesterol, elevated LDL-cholesterol and the predominance of small dense LDL particles. These lipid changes represent the major link between diabetes and the increased cardiovascular risk of diabetic patients. The underlying pathophysiology is only partially understood. Alterations of insulin sen...

Vol. 13, July-September, 2014 Annals of African Medicine Sir, The recent report on dyslipidemia among HIV‐infected patients is very interesting.[1] Muhammad et al., concluded that “HIV‐infected patients on HAART demonstrated higher prevalence of high TC while HAART naïve subject showed higher prevalence of low HDL.[1]” Indeed, the problem of dyslipidemia is well‐known among the HIV‐infected pat...

Emerging evidence suggests that dyslipidemia is an independent risk factor for diabetic neuropathy (DN) (reviewed by Vincent et al. 2009). To experimentally determine how dyslipidemia alters DN, we quantified neuropathic symptoms in diabetic mice fed a high-fat diet. Streptozotocin-induced diabetic C57BL/6 mice fed a high-fat diet developed dyslipidemia and a painful neuropathy (mechanical allo...

Dyslipidemia is an important etiologic factor in the development of cardiovascular disease (CVD), which is a leading cause of death worldwide. As CVD begins in childhood, and as dyslipidemia is an important risk factor for CVD, screening and treatment of dyslipidemia in adolescents and children becomes an important health matter. This review deals with issues related to screening, diagnosis and...

Cardiovascular disease (CVD) is a significant cause of illness, disability, and death among individuals with diabetes. The macrovascular complications of diabetes— Coronary Heart Disease (CHD), Cerebro Vascular Accidents (CVA), and Peripheral Vascular Disease (PVD)— all being different facets of the same vascular damage – account for more than 70% of all deaths in individuals with diabetes. CVD...

Dyslipidemia is a prevalent condition that affects patients infected with human immunodeficiency virus (HIV) who are receiving antiretroviral therapy. These preliminary recommendations summarize the current understanding in this area and propose guidelines for management. Existing guidelines for the management of dyslipidemia in the general population formed the general basis for our recommenda...

BACKGROUND Patients with depression are often nonadherent to therapy for depression and chronic comorbid conditions. METHODS To determine whether improved antidepressant medication adherence is associated with an increased likelihood of chronic comorbid disease medication adherence and reduced medical costs, we conducted a retrospective study of patients initiating antidepressant drug therapy...

OBJECTIVE To evaluate the prevalence and risk factor of dyslipidemia in Thai schoolchildren. MATERIAL AND METHOD A cross section- study of 348 schoolchildren aged 6-17.8 years in Nakork Nayok province, Thailand between May and June 2009 was conducted. Total cholesterol and triglyceride were measured from a 10-hour fasting blood. Dyslipidemia (hypercholesterolemia and/or hypertriglyceridemia) ...

OBJECTIVE Childhood-onset obesity is associated with increased mortality and morbidity related to cardiovascular diseases (CVD) during adulthood. Dyslipidemia has a fundamental role in the pathogenesis of CVD. This study aimed to evaluate the prevalence of dyslipidemia and related factors among obese children and adolescents. METHODS Obese patients aged between 2 and 18 years were included in...

We investigated the relationship between the polymorphism of SOCS-3 and dyslipidemia of people from Uygur in Xinjiang, China. This cross-sectional study included 1379 participants in a Hetian Xinjiang Uygur population who were 30-70 years of age and were not from interracial marriages of 3 generations; all subjects were genotyped (909 dyslipidemia subjects, 470 healthy subjects). Allele (P = 0....