Passive cutaneous anaphylaxis (PCA) was produced in the rat with mouse IgE-rich antiserum. The effect of drugs on the PCA-induced skin histamine decrease and leakage of protein-bound dye was studied. Salbutamol (0.5 mg/kg i.v. or 1.0 mg/kg s.c.) and cromoglycate (10 mg/kg i.v.) significantly inhibited the skin histamine decrease. A combination of salbutamol (0.5 mg/kg i.v. or 1.0 mg/kg s.c.) an...

OBJECTIVE To evaluate the effect of intracoronal bleaching agents on the sealing properties of different intraorifice barriers and root filling materials. STUDY DESIGN The root canals of extracted human premolars (n=180) were prepared by using System GT rotary files and filled with either gutta-percha+AH Plus or Resilon+Epiphany sealer. In both groups, the coronal 3mm of root filling was remo...

OBJECTIVE To evaluate the gingival marginal seal in class II composite restorations using different restorative techniques. MATERIAL AND METHODS Class II box cavities were prepared in both proximal faces of 32 sound human third molars with gingival margins located in either enamel or dentin/cementum. Restorations were performed as follows: G1 (control): composite, conventional light curing te...

BACKGROUND The aim of this study was to quantitatively analyze the amount of dye leakage with AH26, Sealapex and Tubliseal sealers in endodonticaly treated teeth. MATERIALS AND METHODS A total of 36 extracted mandibular molar specimens were divided into three groups; Group I: Sealapex, Group II: Tubliseal, Group II: AH26 with 12 samples in each group. Standard access cavity and biomechanical ...

Introduction: This study compared the apical sealing ability of a bioceramic based root canal repair filling material (iRoot FS) with mineral trioxide aggregate (MTA). Methods and materials: Forty single-canal teeth were prepared and randomly divided into two experimental groups (n=18) and two control groups (n=2). Teeth in experimental groups were retrofilled with either MTA or iRoot FS. After...

The aim of this study was to investigate apical microleakage after use of the Resilon system in comparison with gutta-percha. The materials used were 54 mesial roots of mandibular molars with an apical curvature of 20-40 degrees . The root canals were instrumented with the Prosystem GT(R) and obturated with: Group I: Gutta-percha + Sealer by lateral condensation (n = 25); Group II: Gutta-percha...

Vascular leakage is an important feature of various disease conditions. In vivo optical imaging provides a great opportunity for the evaluation of this phenomenon. In the present study, we focus on the development and validation of a near-infrared (NIR) imaging formula to allow reliable, cost-efficient evaluation of vascular leakage in diverse species using the existing small-animal fluorescenc...

OBJECTIVES The aim of this study was to assess the apical sealing ability of different core materials used with Epiphany(TM) sealer and to evaluate the effect of Resilon/Epiphany(TM) system on creating an apical mono-block seal. METHODS Fifty-five extracted human teeth were used. Forty-five were selected and randomly divided into three groups and ten teeth were used as positive and negative c...

There is controversy as to whether platelet intracellular free calcium ([Ca2+]i) is increased in spontaneously hypertensive rats (SHR) as compared with Wistar-Kyoto (WKY) rats. Discrepant results may be due to methodological problems including platelet activation during the collection process and leakage of intracellular dye used for [Ca2+]i measurement. To provide further insight into this pro...