Oral lichen planus (OLP) is a chronic inflammatory disease of the oral mucosa which is considered by the World Health Organization (WHO) as a premalignant condition. One step in malignant development is so called epithelial mesenchymal transition (EMT), a process whereby epithelial cells acquire mesenchymal characteristics. A factor known to induce EMT is the transforming growth factor-β (TGF-β...

Colonocyte damage in the rectal mucosa in shigellosis is the result of bacterial invasion and leads to ulceration. Additional factors in colonocyte damage may be the Shigella cytotoxin and, especially in colonic crypt cells, bacterial endotoxin. A vascular lesion was present in the lamina propria of the rectal mucosa, which resembled endothelial damage secondary to bacterial endotoxins. In pati...

Rabbits with ligation of the common bile duct, of one and three weeks duration, showed a significant increase of somatostatin content in duodenal mucosa and plasma as compared with control animals. The increase of mucosal somatostatin was associated with a decrease in the binding capacity of both high- and low-affinity binding sites without changes in the affinity values in cytosol of duodenal ...

adenoid cystic carcinoma (adcc) is a malignant neoplasm, which accounts for 5-10% of all salivary gland tumors (1). about 50% of these tumors originate from intraoral minor salivary glands usually in the hard palate (1). three clinically obvious characteristics of adcc include slow growth rate, perineural invasion and high incidence of distant metastasis (1). the most commonly-affected sites of...

squamous cell carcinoma (scc) of the buccal mucosa accounts for 23% to 37% of all intraoral cancers, the prognosis is generally poor. we reported a case of local invasion of buccal squamous cell carcinoma. a 32-year-old man referred to the clinic with a chief complaint of swelling in the right cheek region that initiated from 6 months ago and rapidly grow from one month ago. history of the pati...

We herein report an 11-year-old girl who came to our clinic with a swelling on the genital area of 2 months duration. Dermatological examination of the patient was performed and a pigmented lesion was found on the inner surface of the labium majus of the mucosa. The lesion was well circumscribed and approximately 1 cm in diameter, with homogenous color distribution. The patient was diagnosed as...

Purpose: The purpose of the study was to report four year implant survival rate for immediate placement using socket shield technique. Objectives included evaluation esthetic outcomes and any complications associated with this Material methods: This is a prospective cohort 10 consecutive patients Implant between maxillary first premolars Data were collected (PPD, BOP, PES, buccal width keratini...

background: superficial mucocele presents as small, clear vesicle on noninflamed mucosa. in this study, we report several vesicles on the bucal mucosa of a woman diagnosed as superficial mucocele.case presentation: a 48-year old woman presented with multiple vesicles on her labial mucosa, ventral surface of the tongue, floor of the mouth and palate. a mucosal biopsy was taken from the vesicle. ...

Persistent severe inflammation in colonic mucosa is thought to cause the development of colon cancer in patients with ulcerative colitis (UC). However, predisposing genetic abnormalities have not been identified in this sequence. Using differential display PCR, we isolated cDNA fragments corresponding to mRNAs that were differentially expressed in colitis-associated cancer tissues and mucosa wi...

the partition coefficients (p-values) of certain new potential, stereoselective, reversible, long-acting local anesthetics have been determined in an n-octanol/ phosphate buffer system. these are derivatives of 2-phenoxyethyldialkylamine hydrochloride, and almost all of them are readily soluble in water. their aqueous solutions have shown different absorption maxima, and these have been used qu...