Danggui-Shaoyao-San (DSS), a famous Chinese herbal formula, has been widely used in the treatment of various diseases. Previous studies have shown that DSS produces antidepressant-like effect in rodents. This study aims to investigate the mechanism(s) underlying the antidepressant-like action of DDS. The results showed that DSS treatment significantly antagonized reserpine-induced ptosis in mic...

Today, not only scientists and researchers, but public services and governments as well use DSS (Decision Support System) methods to solve forest policy and management problems in order to meet the multiple needs of the public and to achieve the greatest possible effectiveness. This paper presents and analyses the current trends in emerging DSS applications for the sector of forest policy and m...

Sophisticated decision support systems (DSS) can reduce preventable medical errors. A standalone DSS prototype was built to identify drug-disease mismatches in the electronic medical record (EMR). When drugs fail to match a known problem on the problem list (drug orphans), either the problem list is deficient or the drug was ordered in error. We tested the performance of an integrated DSS proto...

We introduce the need for a distributed guideline-based decision support (DSS) process, describe its characteristics, and explain how we implemented this process within the European Union’s MobiGuide project. In particular, we have developed a mechanism of sequential, piecemeal projection, i.e., 'downloading' small portions of the guideline from the central DSS server, to the local DSS in the p...

The paper presents selected issues related to design and implementation of model based Decision Support Systems (DSS). For over ten years the SDS Program has been involved in cooperation with various projects at IIASA and in collaborating research institutes. This cooperation has resulted in the development of many DSS, which in turn stimulated research on the theory and methodology of decision...

Inflammatory bowel diseases (IBD) result from complex interactions between environmental and genetic factors. Low blood levels of vitamin B12 and folate and genetic variants of related target enzymes are associated with IBD risk, in population studies. To investigate the underlying mechanisms, we evaluated the effects of a methyl-deficient diet (MDD, folate, vitamin B12 and choline) in an exper...

OBJECTIVE To evaluate a system we developed that connects natural language processing (NLP) for information extraction from narrative text mammography reports with a Bayesian network for decision-support about breast cancer diagnosis. The ultimate goal of this system is to provide decision support as part of the workflow of producing the radiology report. MATERIALS AND METHODS We built a syst...

Metabolic profiling of the fecal extracts of male mice was carried out to assess the effects of probiotics on colonic inflammation using (1)H NMR spectroscopy coupled with multivariate data analysis. The control group (n = 5) was administered phosphate buffered saline for 14 days. Acute colitis was induced with dextran sulfate sodium (DSS) for 7 days following administration of phosphate buffer...

Dark Spot Syndrome (DSS) is one of the most common diseases of boulder corals in the Caribbean. It presents as sunken brown lesions in coral tissue, which can spread quickly over coral colonies. With this study, we tested the hypothesis that similar to other coral diseases, DSS is a dysbiosis characterized by global shifts in the coral microbiome. Because Black Band Disease (BBD) was sometimes ...

OSCAR-DSS is a generic decision support system based upon OSCAR—a general-purpose programmable architecture for rational agents. OSCAR-DSS is a partial implementation of that architecture, with some minor modifications to convert it to a decision support system that merely recommends actions rather than performing them. OSCAR-DSS has been further instantiated to produce OSCAR-MDA, a medical dec...