نتایج جستجو برای: drug regimen
تعداد نتایج: 622984 فیلتر نتایج به سال:
Prevalence of Polypharmacy and Correlations with Sex, Age and Drug Regimen in Insurance Prescription
Abstract Simultaneous use of multiple drugs (Polypharmacy, PP) is associated with adverse drug reactions, medication errors, increased risk of hospitalisation and increased curative costs, specially when the number of drugs exceeds four items. This cross-sectional study was conducted to determine prevalence of PP and its some associated factors. Data were derived from health insurance prescrip...
Background and Objectives: To compare pathologic complete response (pCR) in patients with advanced rectal cancer receiving neoadjuvant chemoradiotherapy (NACT) by 5-FU or Xeloda (capecitabine) with and without Eloxatin (oxaloplatin injection). Materials and Methods: Seventy-five consecutive patients with the diagnosis of advanced rectal adenocarcinoma were included. Two basic chemotherapy r...
Twenty human immunodeficiency virus-infected patients experiencing virologic failure of an indinavir- or ritonavir-containing treatment regimen were evaluated in a prospective, open-label study. Subjects received nelfinavir, saquinavir, abacavir, and either another nucleoside analog (n=10) or nevirapine (n=10). Patients treated with the nevirapine-containing regimen experienced significantly gr...
Abstract Background & Aims: patient compliance with therapeutic regimen predicts successful treatment and reduces the severity of negative complications. The aim of this study was determination of relationship between adherence to therapeutic regimen and health related quality of life in hypertensive patients in 2012. Material & Methods: It was a descriptive- correla...
bility profile of a single-class four drug (quadruple) nucleoside reverse transcriptase inhibitor (NRTI) regimen compared with a 2-class standard-of-care regimen. Methodology: A three-centre, randomized, open-label comparative pilot study of zidovudine/lamivudine/efavirenz (triple) versus abacavir/lamivudine/zidovudine/tenofovir (quadruple) therapy in HIV-1-infected, treatment-naive individuals...
Children with tuberculosis are treated with drug regimens copied from adults despite significant differences in antibiotic pharmacokinetics, pathology, and the microbial burden between childhood and adult tuberculosis. We sought to develop a new and effective oral treatment regimen specific to children of different ages. We investigated and validated the concept that target drug concentrations ...
Safety of a rechallenge with an immune checkpoint inhibitor (ICI) after immune-related adverse event (irAE) remains unclear, especially for those patients ICI class switch. All drug reactions involving at least one reported up to December 31, 2021 were extracted from the US Food and Drug Administration Adverse Event Reporting System (FAERS) database. The primary outcome was recurrence initial i...
BACKGROUND The optimal sequencing of antiretroviral regimens for the treatment of infection with human immunodeficiency virus type 1 (HIV-1) is unknown. We compared several different antiretroviral treatment strategies. METHODS This multicenter, randomized, partially double-blind trial used a factorial design to compare pairs of sequential three-drug regimens, starting with a regimen includin...
Antiretroviral drugs have been recommended for postexposure prophylaxis (PEP) after high-risk sexual exposures for more than a decade. Three drug regimens could offer the highest levels of protection, particularly if the infectious source is taking medication, but drug intolerance has often led to suboptimal adherence. The current study evaluated a novel 3-drug PEP regimen, consisting of ralteg...
This research is a descriptive- analytic study which has been conducted inorder to determine the degree of tuberculous patients knowledge of their tubereulosis disease and its relation to therapeutic regimen in Tehran TB control centers.In this research , 120 tuberculous patients calling on tuberculosis control centers in Tehran andbeing under drug therdpyfor about 2-9 months were selected as s...
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