Non-enzymatic glycosylation of proteins is one of the key mechanisms in the pathogenesis of diabetic complications. Glycation of IgG is of special interest due to its possible influence on the functionality of immunoglobulins and overall immuno-competence. The aim of this study was to clarify more details of in vitro glycation of IgG and to study the effect of this modification on its interatio...

In our previous report, we demonstrated that the tyrosine phosphorylation of sperm proteins (TPSP) of guinea pig was associated with capacitation and hyperactivation (CAHA), and Ca and HCO3 were required for the initiation of CAHA and increasing the TPSP. The aim of this study was to further investigate the mechanism underlying the above events. The results showed that addition of cAMP agonists...

conclusions this method can be appropriate to estimate sensitive issues; however, lack of understanding the method or doubting the confidentiality of the responses can lead to bias in the results. that is to say, if the instructions are introduced better, the level of trusting the method will increase and accordingly more reliable responses can be obtained. more studies under controlled conditi...

r f p b T any of surgical techniques have been described for the losure of oroantral fistulaes and most of them rely on mobiizing the soft tissue and advancing the resultant flap into he defect. For this reason, conventional techniques such as; imple vestibular mucosal flaps, rotational pedicled palatinal r buccal flaps or palatinal island flaps are used. In addition o these conventional techni...

Jackal is a Java-based tool for communication using the KQML agent communication language. Some features that make it extremely valuable to agent development are its conversation management facilities, exible, blackboard style interface and ease of integration. Jackal has been developed in support of an investigation of the use of agents in enterprise-wide integration of planning and execution ...

The purpose of this work is to study for small strains, the quasistatic two-body contact problem without friction. The mechanical interation between the bodies is modeled, under the assumption of small displacement, by the bilateral or unilateral contact condition [1]. An algorithm is introduced to solve the resulting finite element system by a non-overlapping domain decomposition method. The g...

the narcotic drugs business find its abusement, nowadays, have been one of the most basic political, economic, health, cultural anti-family disorders in almost all over the world. despite all technologic anti cultural developments, it seems that the tendency and interest of producers, distributors and users of these drugs in all different age levels are growing up increasingly. unfortunately, t...

background microencapsulation is a useful method to prolong a drug release from dosage forms and to reduce its adverse effect (1) among various available methods. the microencapsulation of hydrophilic active ingredients requires the use of a polar dispersing phase such as a mineral oil. acetone/paraffin systems are conventionally used. objectives the current study aimed to investigate two diffe...

results there was significant reduction in anger symptoms of drug-dependent individuals after gross model based emotion regulation training (ert) (p < 0.001). moreover, the effectiveness of the training on anger was persistent in the follow-up period. conclusions symptoms of anger in drug-dependent individuals of this study were reduced by gross model-based emotion regulation strategies trainin...

non-medical use of prescription drugs (also known as medication diversion) is a common problem in middle and low income countries where monitoring capacities and law enforcement mechanisms are not efficiently developed (1-3). prescribed central nervous system (cns) stimulants, sedative hypnotics and long-lasting opioids are the most important drugs diverted throughout the world (1-4). non-medic...