introduction: complete adhesion of the impression materials to trays is important to prevent impression materials from being pulled away from trays during removed from the mouth and to ensure that the direction of polymerization shrinkage will be towards the tray. the aim of this study was to evaluate the effects of two retention features of custom trays (adhesive vs holes) on the dimensional a...

Transdermal drug delivery (TDD) is used to deliver drugs through the skin as an alternative to oral, intravascular, and subcutaneous routes. While there are many advantages to TDD, skin is a very effective barrier and provides resistance to drug delivery. To improve drug delivery through the skin, permeation enhancers are used. We developed an axisymmetric COMSOL Multiphysics model of drug diff...

Background and Aim: Fractured metal-ceramic restorations may be repaired with composite in some cases to postpone the fabrication of a new restoration. Knowledge about the bond strength can help predict the success rate of this treatment modality. The aim of this study was to assess the effect of two types of mechanical surface treatment of metal along with the use of different adhesive systems...

   The objective of the present investigation was to develop and evaluate a contraceptive vagino-adhesive propranolol hydrochloride gel. To achieve this, various mucoadhesive polymers including guar gum (1-4% w/w), sodium alginate (4-7% w/w), xanthan gum (2-5% w/w ), HPMC 4000 (3-5% w/w), Na CMC (4-7% w/w), carbomer 934 and carbomer 940 both in the range of 0.5-2.0% w/w, were dispersed in an aq...

Aim: The objective of the present research work was to formulate and compare two different kinds of penetration enhancer in transdermal patch with placebo patch using a drug (Salbutamol sulphate) and compare for in vitro drug release. Study Design: The transdermal patches of Salbutamol sulphate were prepared by solvent evaporation technique using different ratios of Hydroxy propyl methylcellulo...

introdouction: esthetic demands of patients have led to the introduction of tooth-colored restorations wherecomposite resins are bonded to the enamel using acid etch techniques. total etch adhesion systems are still considered as the gold standard among bonding systems. however, clinicians have a tendency to use adhesive systems with simpler application procedures. the aim of the present study ...