introduction: in a comprehensive health approach, emphasis has been more on education and self-care than care itself, and aims to increase patient’s knowledge to give decision making and independence ability to improve quality of lifestyle. these can develop with progress of information technology. the aim of this study was to evaluate hospital information system (his) in meeting the patient dr...

Nearly all general practitioners meet representatives of drug companies.' The drug industry spent an estimated £5000 per general practitioner promoting its products in the United Kingdom in 1985.2 Drug representatives are a crucial element in the promotion of products, and expenditure on representatives accounts for over 500/o of promotional budgets.' Information is available on the frequency a...

Interactions between drug companies and medical students may affect evidence-based medical practice and patient safety. The aim of this study was to assess drug company-medical student interactions in a medical faculty where limited specific national or institutional regulations apply between drug companies and medical students. The objectives of the study were to determine the exposure and att...

BACKGROUND Phase III clinical trials and Food and Drug Administration (FDA) regulatory decisions are critical for success of new drugs and can influence a company's market valuation. Knowledge of trial results before they are made public (ie, "inside information") can affect the price of a drug company's stock. We examined the stock prices of companies before and after public announcements rega...

In November 2002, the Common Market for Eastern and Southern Africa (COMESA), Africa’s major free trade bloc, applied to the World Trade Organization (WTO) for the right to manufacture low-cost drugs to treat AIDS. The Secretary General of the Organization Erastus Mwencha, in announcing this move, said that drugs must be cheaper as the world could not continue to see people dying for the sake o...

In 1987, a group infection of hepatitis in patients receiving a contaminated fibrinogen product was first reported to the Japanese regulatory agency. Eventually, this serious drug incident involved more than 10,000 cases of infection. In response, the Government of Japan established a responding inspection committee in 2008 to make recommendations for the restructuring of drug regulatory admini...

Over the course of the last decade, atypical antipsychotic medications (olanzapine, quetiapine, and risperidone) have become first-line choices for acute and maintenance treatment for schizophrenia. In numerous cases, these antipsychotics have replaced typical neuroleptics, which are associated with a high incidence of adverse effects, particularly parkinsonism and tardive dyskinesia. Each phar...