Muscle biopsy specimens with a pronounced inflammatory component were evaluated for myocyte expression of class II histocompatibility antigens (HLA-DR) by immunohistochemical techniques. All 15 cases of polymyositis were positive; six cases of muscular dystrophy (two Duchenne, four facio-scapulo-humeral), and one case of acute denervation (motor neurone disease) were negative, despite having a ...

A hurdle to EMR-based studies is the characterization and extraction of complex phenotypes not readily defined by single diagnostic/procedural codes. Here we developed an algorithm utilizing data mining techniques to identify a diabetic retinopathy (DR) cohort of type-2 diabetic African Americans from the Vanderbilt University de-identified EMR system. The algorithm incorporates a combination o...

This is an admirable little monograph from an admirable series of little volumes. Not merely the layman, but also the medical man and the research worker will be interested in Dr Singers well written, carefully compiled and useful little book. Commencing with ancient days he reviews in turn Aristotle s viewswho regarded the heart as the seat of intelligence and the source of bodily heat; the vi...

Author Disclosure Drs Hellström-Westas, Rosén, and de Vries have been involved in development or testing of the instruments (BrainZ [BrainZ Instruments Ltd, Auckland, New Zealand], Olympic 6000 [Olympic Medical, Seattle, Washington], and Nervus Monitor [Viasys, Nicolet Biomedical, Madison, Wisconsin]) from which records are shown in this article. None has an economic interest in the production ...