Results: The overall wastage factor for BCG vaccine was 1.83, for OPV was 1.33, for DPT was 1.19, for Hepatitis B vaccine was 1.26 and for Measles vaccine was 1.39. The WF was highest for sessions held at ICDS for BCG vaccination (3.38) followed by sessions held at mobile sites for BCG vaccination (2.50). The WF was lowest for sessions held at UHC for DPT vaccination (1.11) followed by sessions...

Current cochlear implant processors poorly represent sound waveforms in the temporal discharge patterns of auditory-nerve fibers (ANFs). A previous study [Litvak et al., J. Acoust. Soc. Am. 114, 2079-2098 (2003)] showed that the temporal representation of sinusoidal stimuli can be improved in a majority of ANFs by encoding the stimuli as small modulations of a sustained, high-rate (5 kpps), des...

INTRODUCTION To evaluate the efficacy of Daptomycin (DPT) lock therapy in the treatment of Grampositive long-term catheter-related bloodstream infections (LT-CRBI). PATIENTS AND METHODS A retrospective review of all patients receiving DPT lock therapy for the treatment of LT-CRBI from December 2009 to May 2010 was conducted. The primary endpoint used in this study was failure to cure the epis...

Full-length tissue factor pathway inhibitor (TFPI) is assumed to be biologically more important than truncated TFPI because of its stronger anticoagulant effect in the diluted prothrombin time (dPT) assay. We have developed a dPT-based assay for TFPI anticoagulant activity. Here, we report the effect of hormonal state on TFPI anticoagulant activity and whether TFPI anticoagulant activity assess...

The catalytic r81e of thiaminoproteins in intermediary carbohydrate metabolism has long been recognized. Although numerous theories have been advanced to explain the chemical mechanism by which the diphosphothiamine (DPT) moiety of thiaminoproteins contributes to the catalytic properties of these enzymes, the modus operandi of DPT has remained unsolved. Perhaps the main reason for this has been...

Many modern cochlear implants use sound processing strategies that stimulate the cochlea with modulated pulse trains. Rubinstein et al. [Hear. Res. 127, 108 (1999)] suggested that representation of the modulator in auditory nerve responses might be improved by the addition of a sustained, high-rate, desynchronizing pulse train (DPT). In addition, activity in response to the DPT may mimic the sp...

Rubinstein et al. [Hear. Res. 127, 108-118 (1999)] suggested that the neural representation of the waveforms of electric stimuli might be improved by introducing an ongoing, high-rate, desynchronizing pulse train (DPT). A DPT may desynchronize neural responses to electric stimulation in a manner similar to spontaneous activity in a healthy ear. To test this hypothesis, responses of auditory-ner...

BACKGROUND Early childhood immunizations have been viewed as promoters of asthma development by stimulating a T(H)2-type immune response or decreasing microbial pressure, which shifts the balance between T(H)1 and T(H)2 immunity. OBJECTIVE Differing time schedules for childhood immunizations may explain the discrepant findings of an association with asthma reported in observational studies. T...