The aim. To develop an EIS method for study the interaction between medicinal products and metal salts on example of Doxycycline iron (III) interaction.
 Materials methods. Measurements total impedance studied solutions have been performed using a vector circuit analyzer ZNB40 (Rohde & Schwarz, Germany). calculations electrical models were software package EC-Lab V10.40. Measurement ce...

The local delivery of antibiotics in the treatment of infectious respiratory diseases is an attractive alternative to deliver high concentration of antimicrobials directly to the lungs and minimize systemic side effects. In this study, inhalable microparticles containing doxycycline hyclate, sodium carboxymethylcellulose, leucine and lactose were prepared by spray drying of aqueous ethanol form...