Objectives: The development of social skills, especially skills in relating to peers, is an important capacity that provides the foundations for lifelong success. Some children with disabilities need to learn social skills more directly. The purpose of this study was to determine the effects of social skills training on socialization skills development in children with Down syndrome. Methods...

Predictors of productive and receptive language development in 39 children with intellectual disabilities (17 with Down syndrome) and their parents were identified. Children were in the prelinguistic or first stage of productive language acquisition (Brown, 1973). The Down syndrome and non-Down syndrome groups were matched on several variables, including IQ, CA, and vocabulary level. After cont...

objective: the purpose of this study was to examine the impact of early family-centered psychological and educational interventions on adaptive behaviors in children with down syndrome (ds). method: utilizing an experimental pretest-posttest control group design, parents of 36 children with ds were selected in isfahan. vineland adaptive behavior scale was used to assess adaptive behavior. resul...

Children with Down syndrome are at an increased risk for engaging in challenging behaviour that may be part of a behavioural phenotype characteristic of Down syndrome. The methodology of applied behaviour analysis has been demonstrated effective with a wide range of challenging behaviours, across various disabilities. Applications to children with Down syndrome and the examination of behavioura...

Children with Down syndrome are at high risk for acute respiratory distress syndrome. In Down syndrome, both regulation of inflammation and apoptosis, important in acute respiratory distress syndrome pathophysiology, are abnormal. This has been linked to an imbalance in free radical scavengers. We investigated the expression of free radical scavengers and the effect of oxidative stress in terms...

BACKGROUND Children with Down syndrome have unique immune profiles and increased leukemia susceptibility. METHODS Mothers of 158 children with Down syndrome diagnosed with acute leukemia at 0 to 19 years in 1997 to 2002 and 173 children with Down syndrome but no leukemia were interviewed. Associations were evaluated via multivariable unconditional logistic regression. RESULTS No association...