introduction: multiple fields and presence of heterogeneities create complex dose distributions that need three dimensional dosimetry. in this work, we investigated mr-based magic gel dosimetry as a three-dimensional dosimetry technique to measure the delivered dose to bladder and rectum in prostate radiation therapy. materials and methods: a heterogeneous slab phantom including bones was made....

PURPOSE To quantify the radiation doses received by the heart and coronary arteries from contemporary tangential breast or chest wall radiotherapy. METHODS AND MATERIALS Fifty consecutive patients with left-sided breast cancer and 5 consecutive patients with right-sided breast cancer treated at a large United Kingdom radiotherapy center during the year 2006 were selected. All patients were ir...

Using internal fiducial markers and electronic portal imaging (EPID) to realign patients has been shown to significantly reduce positioning uncertainties in prostate radiation treatment. This creates the possibility of decreasing the planning target volume (PTV) margin added on the clinical target volume (CTV), which in turn may allow for dose escalation. We compared the outcome of two plans: 7...

The Monte Carlo calculation of dose for radiotherapy treatment planning purposes introduces unavoidable statistical noise into the prediction of dose in a given volume element (voxel). When the doses in these voxels are summed to produce dose volume histograms (DVHs), this noise translates into a broadening of differential DVHs and correspondingly flatter DVHs. A brute force approach would enta...

BACKGROUND Much research has widely been conducted into thyroid hormones levels following radiotherapy for breast cancer. Consequently, in this study, we evaluated to relate the rate of thyroid hormones levels with the dose distribution among breast cancer patients. MATERIAL AND METHODS Thirty patients were treated with 4-field breast cancer radiotherapy. The dose volume histograms, the volum...

PurposeNormal tissue complication probability (NTCP) models could aid the understanding of dose dependence radiation-induced toxicities after eye-preserving radiotherapy choroidal melanomas. We performed NTCP-modeling and established dose-response relationships for visual acuity (VA) deterioration common late complications treatments with proton therapy (PT).DesignRetrospective study from singl...

Background: Purpose of the study is to evaluate field-in-field (FIF) and sliding-window intensity modulated radiation therapy (SW-IMRT) treatment plans in terms of homogeneity index (HI), conformity index (CI) and normal tissue doses for organs at risk (OAR) in patients with endometrial carcinoma along with deriving a new expression for CI. Materials and Methods: Four different FIF plans with d...