The accuracy with which 123I activity is measured by a dose calibrator depends on the composition and geometry of the source. The present study assessed the variability of current commercial dose calibrators in assaying liquid 123I samples. Methods: A calibration procedure for 123I measurement was performed on 177 dose calibrators (11 manufacturers) at 138 sites in North America and Europe. Usi...

Precise calibration of kilometer-scale interferometric gravitational wave detectors is crucial for source localization and waveform reconstruction. A technique that uses the radiation pressure of a power-modulated auxiliary laser to induce calibrated displacements of one of the ∼10 kg arm cavity mirrors, a so-called photon calibrator, has been demonstrated previously and has recently been imple...

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Lung microdialysis has been used with rats to investigate antibiotic distribution after single-dose administration. However, conducting such experiments after intravenous infusion at steady state would constitute a more convenient alternative, which was evaluated here, using levofloxacin (LVX) as a test compound. Microdialysis probes were inserted in blood and muscle, used as a comparator, betw...

A new procedure is provided for transferring analyte concentration values from a reference material to production calibrators. This method is robust to calibration curve-fitting errors and can be accomplished using only one instrument and one set of reagents. An easily implemented stochastic approximation algorithm iteratively finds the appropriate analyte level of a standard prepared from a re...

BACKGROUND The availability of commutable calibrator materials may ease considerably the task of harmonizing assay results and ensuring their traceability to reference procedures. We sought to verify the commutability of potential calibrator materials and evaluate their effectiveness in harmonizing LDH results by 2 measurement methods. METHODS We measured LDH in 109 serum samples and 31 mater...

Insulation is a crucial phenomenon for high voltage apparatus. Partial discharge activity affects the service life of the dielectrics. Therefore partial discharge must be less than a specified value for high voltage equipment. An accurate partial discharge measurement strongly depends on scaling of the measurement systems. It is a general method to use a partial discharge calibrator to calibrat...

Telomere length (TL) is increasingly being used as a biomarker in epidemiological, biomedical and ecological studies. A wide range of DNA extraction techniques have been used in telomere experiments and recent quantitative PCR (qPCR) based studies suggest that the choice of DNA extraction method may influence average relative TL (RTL) measurements. Such extraction method effects may limit the u...

by spectrophotometer, readings for all samples were higher than those for the 0 ng/L calibrator; OOM extracts provided signals that were well above those of the 400 ng/L calibrator. In summary, simple aqueous extracts from small portions of 6 different OOM-associated tumors revealed very high FGF-23 concentrations as assessed by the calibrator assay; FGF-23 concentrations were also readily dete...

This paper deals with the metrological management of an acquisition system that has been developed for monitoring an experimental PhotoVoltaic (PV) plant. The acquisition system has been conceived for comparing the performance of different PV technologies and for verifying the nominal specifications of the PV modules. For these reasons, the traceability of the monitoring system has to be ensure...