نتایج جستجو برای: dna fragmentation index
تعداد نتایج: 922260 فیلتر نتایج به سال:
Background: Micronutrients in support to the carbon cycle were shown to reduce sperm DNA damage both in animal models and infertile men. Besides supporting DNA methylation, their positive effect may be mediated by an improved performance of the endogenous antioxidant system but this has not yet been proven in clinical settings. The present study aimed at evaluating the effects of micronutrient ...
OBJECTIVE The study aimed to evaluate the feasibility and reproducibility of measuring phospholipase C zeta (PLCζ) using immunostaining in human sperm and to investigate the relationship between PLCζ immunoreactivity and DNA fragmentation and oxidation in human sperm. METHODS Semen samples were obtained from participants (n=44) and processed by the conventional swim-up method. Sperm concentra...
s:1993:"Background: There are many approaches that gene expression is controlled in eukaryotes. DNA methylation is one of several epigenetic mechanisms that cells use to control gene expression and lock genes in the "off" position. In addition, sperm DNA damage can correlate with DNA methylation defect. There is evidence that sperm of infertile men contain more DNA damage than fertile men and t...
Background and purpose: Turmeric (Curcuma longa L.) has received much interest by researchers due to numerous biological properties. The aim of this study was to compare the anticancer and antioxidant properties of turmeric extracts on colon cancer cells Caco-2 and to survey DNA fragmentation by the extracts. Materials and methods: In order to investigate the cytotoxicity and antioxidant prope...
Background and Aim: Sperm cryopreservation is a common technique used for management of male infertility. But this method has detrimental effects on sperm DNA and chromatin quality. Evaluation of different markers associated with the health of genetic material of sperm is beneficial for determination of the fertility of sperm. The aim of this study was to assess the effect of sperm chromatin co...
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