Technetium-99m dimercaptosuccinic acid (DMSA) scan was performed on a 32-year-old woman with 
 abdominal pain. A normal functioning slightly ptotic right kidney seen planar images. There no activity in the left renal region and small fusiform pelvic area. Pelvic computed tomography (CT) axial images revealed pre-vesical abscess pushing bladder posteriorly to side. On obtained after percuta...

Extrarenal uptake of 99mTc-DMSA is a rare finding, which has been described in some unusual conditions as bone metastasis, aortic aneurysm and hemangioma. The purpose of this report is to present two cases of abnormal 99mTc-DMSA uptake in the lungs, which remained unexplained even after radiologic assessment.

In the overall long-term management of lead poisoning, chelation therapy can have short-term benefits; however, these benefits must be accompanied by drastic reduction in environmental exposure to lead if therapy is to have any long-term benefit. This discussion is limited to calcium disodium ethylenediaminetetraacetate (CaNa2EDTA), the chelating agent that has been the mainstay of treatment of...

This study compares the accuracy of 99mTc(V)-dimercaptosuccinic acid (99mTc(V)-DMSA) Single Photon Emission Computer Tomography (SPECT) by intravenous or local injection in the detection of occult cervical lymph node metastases in clinically N0 squamous cell carcinoma of the oral cavity. Fifty-eight previously untreated patients without clinically detectable cervical metastases were included in...

Cysteine (Cys) and homocysteine (Hcy)-S-conjugates of inorganic mercury (Hg2+) are transportable species of Hg2+ that are taken up readily by proximal tubular cells. The metal chelators, 2,3-dimercaptopropane-1-sulfonic acid (DMPS) and meso-2,3-dimercaptosuccinic acid (DMSA), have been used successfully to extract Hg2+ from these cells, presumably via the multidrug resistance protein (Mrp2). In...

2, 3-Dimercaptopropane-1-sulfonic acid (DMPS) and meso-2, 3-Dimercaptosuccinic acid (DMSA) are dithiols used to treat humans exposed to methylmercury (CH(3)Hg(+)). After treatment, significant amounts of mercury are eliminated rapidly from the kidneys and are excreted in urine. In the present study, we extended our previous studies by testing the hypothesis that MRP2 mediates the secretion of D...

We present a patient with left-sided obstructed megaureter secondary to neuropathic bladder. He was referred for technetium-99m dimercaptosuccinic acid ((99m)Tc-DMSA) renal cortical scintigraphy to evaluate renal cortical function. Images obtained 4 hr after injection showed significant activity in the dilated left ureter. When the ureter is visualized on DMSA scan, obstructive megaureter shoul...

OBJECTIVE To determine total lead body burden by the Lead mobilization test (LMT) by measuring 4 hours urinary lead excretion in the lead exposed as compared to unexposed industrial workers after administration of 10 mg/Kg of dimercaptosuccinic acid and correlate it with blood lead levels, at Wah district Rawalpindi. METHODS Total 149 males consisting of 87 lead exposed workers and 62 control...

background renal scintigraphy with technetium 99m labeled dimercaptosuccinic acid (99mtc-dmsa) is a traditional imaging technique commonly used to detect renal scar in patients with probable vesicoureteral reflux (vur) and/or urinary tract infection (utis). we determined whether normal results of dmsa renal scan obviate the need for voiding cystourethrography (vcug) in evaluating children with ...