A 19-year-old woman presented to her general practitioner with a purpuric rash 3 weeks after receiving her first 150 mg intramuscular injection of depot medroxyprogesterone acetate (DMPA) at a family planning clinic. She had no medical or family history of note and was taking no other medication. Following investigation by the haematology department she was diagnosed with thrombocytopenic purpu...

Reported is a case of life-threatening septic shock that occurred in an otherwise healthy host after administration of a peripheral venous infusion of a solution contaminated with Ochrobactrum anthropi, an unusual human pathogen. The rapid onset of shock may have been due to a large inoculum caused by nonsterile practices at the time of reconstitution.

st st between 1 of January 2004 and 31 of December 2013 is presented. This was a descriptive retrospective study aimed at establishing the acceptance, safety and effectiveness in our population. Information on socio-demographic characteristics, source of primary information, complications and accidental pregnancies were obtained from clients. Case files entered into Microsoft excel and analyzed...

background & aim: sexual health is an essential element of quality of life, affecting both physical and psychological domains. hormones used in contraceptive methods have contradictory effects on sexual function. in this study, we aimed to compare sexual function in women using combined oral contraceptives (coc) and depot medroxyprogesterone acetate (dmpa), referred to healthcare centers affili...

Depot medroxyprogesterone acetate (DMPA) is a commonly used form of contraception, with noncontraceptive benefits for the user. The mode of action is through the suppression of ovulation. It leads to hypoestrogenism which causes dryness of the vagina and dyspareunia. We present in this paper a patient that was very symptomatic with regard to vaginal atrophic changes determined by vaginal cytolo...

implant and DMPA appears increasingly important in light of one recent animal study suggesting a relationship between progestin exposure and vaginal atrophy (which might lead to increased risk of HIV infection).6 Although it is premature to extrapolate the findings of this study to humans, the results highlight the importance of correct and consistent condom use among users of hormonal contrace...

BACKGROUND Abnormal uterine bleeding is commonly associated with progestin-only contraceptives, including depot medroxyprogesterone acetate (DMPA), and remains the main reason why these agents are discontinued. Matrix metalloproteinases (MMP), enzymes which degrade specific extracellular matrix components, and leukocytes are implicated in menstruation. Alteration in endometrial MMP-9 and leukoc...

This retrospective study looked at the bone mass density of women using combined oral contraception (n = 59), depot-medroxyprogesterone acetate (DMPA) (n = 34) or controls (n = 62) who had not used steroid contraception for 6 months. The groups were matched for body mass index, age, smoking, alcohol consumption, caffeine consumption and exercise. There was no matching for family history nor was...

In the title centrosymmetric dinuclear complex, [Tm(2)(C(10)H(11)O(4))(6)(C(12)H(8)N(2))(2)], the unique Tm(III) ion is coordin-ated by five 3,4-dimethoxy-phenyl-acetate (DMPA) ligands and and a bis-chelating 1,10-phenanthroline (phen) ligand via seven O atoms and two N atoms, forming a distorted tricapped trigonal-prismatic environment. The DMPA ligands coordin-ate in the bis-chelate, bridging...