The regioselective ring opening of styrene oxide using elemental iodine and bromine in the presence of disulfides as new catalysts was studied. The conductivity titration and UV spectroscopy were used to study the interaction of iodine with these catalysts. The results indicate that disulfide 11 is efficient in polyiodide formation, and can catalyze this reaction in excellent yield and high reg...

Aim: Testicular torsion which is the most common cause of acute scrotum, a real surgical emergency. However, despite imaging techniques and laboratory studies used in differential diagnosis pathologies causing difficult. Therefore, there need for parameters that confirm testicular torsion.In our study, we aimed to investigate usability as parameter scrotum inflammation children via thiol-disulf...

Due to the significance of disulfide bonds within modern material and medicinal sciences, this review provides an overview disulfide-containing polymers that can be obtained by chain-growth polymerization monomers.

The objective of this study was to compare the modulatory effect of garlic oil and its three organosulfur compounds, diallyl sulfide (DAS), diallyl disulfide (DADS), and diallyl trisulfide (DATS), on rat hepatic detoxification enzyme activity, and protein and mRNA expression. Rats were orally administered garlic oil (80 or 200 mg/kg bw), DAS (20 or 80 mg/kg bw), DADS (80 mg/kg bw), or DATS (70 ...

tissue plasminogen activator (tpa) is a serine protease, which is composed of five distinct structural domains with 17 disulfide bonds, representing a model of high-disulfide proteins in human body. one of the most important limitations for high yield heterologous protein production in escherichia coli (e. coli) is the expression of complex proteins with multiple disulfide bridges. in this stud...

the manipulation of redox potential in secretory pathway by thiol reducing agents can be a strategy to improve the production levels of disulfide-bonded proteins including recombinant antibodies. here we have studied the influence of cysteamine on viability and the production level of igg4 in sp2.0 cells. for this purpose, the recombinant sp2.0 cells producing an anti cd33 igg4, were subjected ...

BACKGROUND Glutathione concentration in the lens decreases in aging and cataractous lenses, providing a marker for tissue condition. Experimental procedures requiring unfrozen lenses from donor banks rely on transportation in storage medium, affecting lens homeostasis and alterations in glutathione levels. The aim of the study was to examine the effects of Optisol-GS and castor oil on lens cond...

Objective: Migraine is a common disease in childhood. Oxidative stress has been implicated the pathogenesis of migraine. Dynamic thiol/disulfide homeostasis proven to be marker oxidative stress. We aimed investigate correlation between migraine and dynamic homeostasis. Material Methods: A total 141 children (71 migrain 70 controls) were included. The serum thiol, native disulfide levels measure...

The effects of protein concentration and blending a phospholipid-rich whey coproduct, Procream (Salibra 700 Procream, Glanbia Nutritionals), with intact or hydrolyzed concentrate, on fish oil microencapsulation efficiency oxidative stability were assessed. Trypsin protease M, from Aspergillus oryzae, used to produce 2 unique hydrolysates. All microcapsules had excellent encapsulation efficienci...