Healthy siblings of schizophrenia patients have an almost 9-fold higher risk for developing the illness than the general population. Disruption of white matter (WM) integrity as indicated by reduced fractional anisotropy (FA) derived from diffusion tensor imaging (DTI), is believed to be the key substrate of schizophrenia. However, it remains unclear whether schizophrenia patients and their hea...

in this study, the effect of irrigation regimes and plant nutrition were evaluated as split plot arrangment based on randomized complete block design with three replications in 2010. treatments consisted of irrigation regimes at three levels: well-irrigation, irrigation disruption at vegetative growth stage, and irrigation disruption at reproductive growth stage as main plots and combination of...

BACKGROUND Previous studies suggest that the transient receptor potential vanilloid 1 (TRPV1) channel has a role in sepsis, but it is unclear whether its effect on survival and immune response is beneficial or harmful. METHODS We studied the effects of genetic (Trpv1-knockout vs. wild-type [WT] mice) and pharmacologic disruption of TRPV1 with resiniferatoxin (an agonist) or capsazepine (an an...

We examine the optimal disruption of dark (covert and illegal) networks. Of central importance is that an interventionist will generally have incomplete information about the dark network’s architecture. We derive the optimal disruption strategy in a stylized model of dark network intervention with incomplete information and show how it combines features of two types of disruption considered in...

Dependent problem drinking, marital disruption and depressive symptoms of sons and daughters of alcohol abusers are examined in a representative sample of 1,772 adults in the United States. Controlling for the sociodemographic characteristics of the adult sons and daughters in logistic regression analyses and for the alcohol-related problems (e.g., alcohol dependence) of the sons and daughters ...

PURPOSE To review the mechanisms of sedative-hypnotic action with respect to the risk of delirium imparted by drugs that act on γ-amino-butyric-acid type A receptors or α(2) adrenoceptors. SOURCE MEDLINE was searched for relevant articles. PRINCIPAL FINDINGS Development of the acute confusional state of delirium is associated with longer intensive care unit (ICU) and hospital lengths of sta...

Ureteropelvic junction (UPJ) disruption seldom occurs in patients with blunt abdominal trauma. The diagnosis of UPJ disruption is delayed in more than 50% of patients, and it can lead to difficulty in further treatment or increase the risk of nephrectomy. We present a 25-year-old man who was found to have left UPJ disruption 2 months after blunt abdominal trauma and who was successfully treated...

With the emergence of environmental protection as a global issue, implementing environmental practices for sustaining green supply chain management (GSCM) has received a lot of attention. This study investigates the impact of integration with suppliers and supply disruption risk on environmental practices. It also examines the role of supplier integration and supply disruption risk on performan...