Drug delivery systems are becoming increasingly sophisticated as pharmaceutical scientists acquire a better understanding of the physicochemical and biochemical parameters pertinent to their performance. Over the three decades, orally disintegrating tablets (ODTs) have gained considerable attention as a preferred alternative to conventional tablets and capsules due to better patient compliance....

The research presented in this thesis focuses on the synthesis of three amphiphilic block copolymer systems containing poly(ethylene oxide) (PEO) blocks. The polymer systems were developed for use in biomedical applications. The first of these is a series of poly(ethylene oxide-b-oxazoline) (PEO-b-POX) diblock copolymers for use in the progress towards novel nonviral gene transfer vectors. Poly...

Zinc treatment is now recommended by the World Health Organization as part of the routine management of acute childhood diarrhoea. A dispersible zinc tablet formulation was developed taking into account the taste, cost, and feasibility to distribute and store. Only limited information is available on the acceptability of and adherence to dispersible zinc tablet. No study has formally assessed w...

We report rational design of amphiphilic polymers capable of making carbon nanotubes (CNTs) highly water dispersible and resistant to biofouling; such CNTs can be conjugated with bioactive molecules so as to be potential drug delivery vehicles.

A robust water-in-oil microemulsion method of making water-dispersible ultra-small (<30 nm) size fluorescent chitosan nanoparticles is reported for the first time and specific targeting of these FCNPs to human leukemia cells via aptamer recognition is demonstrated.

Water-dispersible and magneto-responsive carbon nano test tubes with a controlled length (1.3 microm) and diameter (35 nm) were synthesized by using the nanochannels of anodic aluminium oxide as a template.

the aim of this paper is to design a fractional order sliding mode controllers (fosmc)for a class of dc-dc converters such as boost and buck converters. firstly, the control lawis designed with respect to the properties of fractional calculus, the design yields an equiv-alent control term with an addition of discontinuous (attractive) control law. secondly, themathematical proof of the stabilit...

The aim of the present study is to formulate and evaluate the Immediate release oral dispersible film formulation of lornoxicam with different ratios polymeric combinations by the solvent evaporation technique. . Lornoxicam, a potent non-steroidal antiinflammatory drug (NSAID) with shorter half life, makes the development of immediate release dosage forms extremely advantageous. These formulati...

A new synchronous rectifier (SR) driving method is proposed using primary current sensing in this paper. Because the magnetizing current of transformer is included in primary winding of transformer, it can’t be used to generate the driving signals of SRs directly. A current compensating winding in current transformer is used to cancel out the magnetizing current and generate suitable driving si...