We describe a patient with discoid lupus erythematosus whose pattern of disease evolved into a systemic vasculitis polyarteritis nodosa.

DLE: discoid lupus erythematosus MEP: milia en plaque INTRODUCTION Milia are small benign superficial keratinous cysts, measuring 1 to 4 mm in diameter. Milia can be primary, appearing spontaneously, or secondary to trauma, skin disease, or medication. Milia en plaque (MEP) is a rare form of this condition characterized by numerous aggregated milia on an erythematous plaque. Discoid lupus eryth...

introduction systemic lupus erythematous (sle) is among rheumatic diseases of unknown etiology. fever of unknown origin (fuo) has been rarely reported to be the presenting sign of sle. presence of four or more sle criteria is diagnostic for the disease. however, presentations may occur serially which make it much more difficult to diagnose an already questioned fuo. case presentation our case o...

man with a chief complaint of right medial knee pain for the past 4 months. The symptoms were insidious in onset, and the patient denied any history of trauma or locking of the knee. Despite physical therapist intervention for a month, which included manual physical therapy and therapeutic exercise, the patient’s right knee pain continued to progressively worsen to the point where normal activi...

The existence of abnormal-shaped menisci has been long recognized. The presence of discoid menisci in the human knee is considered to be a congenital malformation with a very low rate of incidence except in Asian populations. Since the publication of Watanabe's Atlas, three types of lateral meniscal abnormalities are generally accepted: the complete and incomplete discoid, as well as the Wrisbe...

Although thalidomide is a U.S. Food and Drug Admistration (FDA) approved medication for erythema nodosum leprosum and multiple myeloma, it has many off-label uses, including for discoid lupus erythematosus (DLE), Behçet's disease, apththous ulcers in HIV patients, and prurigo nodularis. Herein, we present a patient with an overlap of discoid lupus erythematosus and lichen planus who was success...

DLE: discoid lupus erythematosus SCC: squamous cell carcinoma SLE: systemic lupus erythematosus UV: ultraviolet INTRODUCTION The incidence of skin cancer is rare in African Americans; however, there are several reports of patients with depigmented or hypopigmented lesions on sun-exposed areas, such as the scalp, who are at increased risk for squamous cell carcinoma (SCC). Decrease in melanin, i...