Biological plausibility is an essential stage in establishing the therapeutic value of a preventive or curative agent. Ultimately, efficacy and effectiveness are tested in clinical trials and community programme evaluations, which provide reassurance and guidance for potential users. Almost invariably, biological plausibility is demonstrated before clinical evaluations are sanctioned and undert...

This study evaluated the use of the American Medical Association (AMA) impairment guides and Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire in U.S. military casualties recovering from burn injury to the hand. Study sample included patients with burns to at least one hand and complete evaluations of impairment and disability upon discharge from the hospital and at a follow-up v...

Since the Supreme Court ruled in Atkins v. Virginia (2002) that intellectually disabled defendants cannot be executed, approximately 7% of death row inmates have filed habeas petitions claiming to have an intellectual disability (Blume, Johnson, & Seeds, 2009). Countless other defendants have been evaluated pre-trial to determine the appropriateness of an Atkins exclusion of the death penalty. ...

BACKGROUND AND PURPOSE The purpose was to investigate the occurrence of self-reported falls in people with stroke at 3, 6, and 12 months and 6 years post stroke and predictors for falls during 6 years. METHODS A prospective study involving 121 people with stroke. Data were obtained through structured interviews and assessments. Generalized estimating equation modeling using proportional odds ...

The aim of the study was to compare the effect ofwater-based exercise in thermal mineral water versus land-based exercise therapy on the lumbar spine range of motion and physical disability in adult patients with chronic low back pain. Out of 72 patients hospitalized for inpatient treatment in a special rehabilitation hospital, 36 patients performed a 3-week standardized program of group water-...

PURPOSE The purpose of this article is to estimate the effect of obesity on both the length of life and length of nondisabled life for older Americans. DESIGN AND METHODS Using data from the first 3 waves of the Asset and Health Dynamics Among the Oldest Old (AHEAD) survey, this article develops estimates of total, active, and disabled life expectancy for obese and nonobese older men and wome...

Abstract Objective The mini-Balance Evaluation Systems Test (BESTest) is a balance measure for assessment of the underlying physiological systems control in adults. Evaluations test–retest reliability mini-BESTest larger samples people with multiple sclerosis (MS) are lacking. purpose this study was to investigate total and section sum scores individual items mild moderate overall MS disability...

Objective: Fragile X syndrome is the second etiology for inherited mental retardation. It may concomitant with other psychiatric disorders. Intellectual disability (ID) is a state of functioning that typically begins in childhood and is characterized by limitations in intelligence and adaptive skills. We intend to introduce a male young patient with Fragile X syndrome and Obsessive-Compulsive d...

Research into access to and experiences with healthcare services of gender-diverse trans individuals remains scarce. In this paper, self-reported general trans-specific were analyzed for differences between people, men, women, using data from a five-country survey. More than half all respondents indicated they had delayed at least once because their gender identity, mostly out fear being treate...

BACKGROUND The high costs of health and social care support for stroke survivors, and the development of new service arrangements, have concentrated growing attention on economic issues. However, there are few data on costs and their association with levels of disability. METHODS Secondary analyses of data from the OPCS (Office of Population Censuses and Surveys) Surveys of Disability conduct...