S EVERAL RECENT REPORTS have incriminated reticulocytes as the cause of “false positive” Coombs tests obtained in spontaneous or experimentally induced anemia.14 As reticulocytosis is frequently associated with the spontaneous Coombs positive hemolytic anemia which develops in NZB mice, and because the positive Coombs test has been used by Holmes and Burnet5T as the main basis for calling the c...

The present study was carried out to assess the efficacy of microtiter method of direct antiglobulin test in diagnosis of Immune Mediated Haemolytic Anaemia in Dogs. Two hundred and fifty eight anaemic dogs with pale/icteric mucous membrane were used for the present study. Initial screening of these dogs was done with saline agglutination test. Forty seven dogs were found positive for saline ag...

By HAL CRAWFORD, B.SC., MARIE CUTBUSH, B.Sc., AND P. L. M0LLI50N, M.D., M.R.C.P. T HE DIAGNOSIS of hemolytic disease of the newborn is made by demonstrating incompatibility between the mother’s serum and the infant’s red cells, associated w-ith signs of red cell destruction in the infant . When the disease is due to anti-Rh itis not uncommoui to find evidence of serologic incompatibility, inclu...

Object. We present here the case of severe fetal anemia caused by anti-E antibody positive, which showed a favorable course only with fetal intraperitoneal administration of immunoglobulin. Case. The mother was 31 years old, blood type B Rh : CCDee, gravida 1, with no history of transfusion. Anti-E antibody was detected in the maternal cross-match test at the 18th gestational week. In percutane...

By HAL CRAWFORD, B.SC., MARIE CUTBUSH, B.Sc., AND P. L. M0LLI50N, M.D., M.R.C.P. T HE DIAGNOSIS of hemolytic disease of the newborn is made by demonstrating incompatibility between the mother’s serum and the infant’s red cells, associated w-ith signs of red cell destruction in the infant . When the disease is due to anti-Rh itis not uncommoui to find evidence of serologic incompatibility, inclu...

BACKGROUND Different serological tests are used in serologic diagnosis of brucellosis. The most widely used of these are Standard Tube Agglutination and Coombs anti-brucella tests. Whereas ELISA Ig M and Ig G tests have been in use for a long time, immuncapture agglutination test has been recently introduced and used in serological diagnosis. The aim of this study was to compare diagnostic valu...

During the last ten years the extraction of specific antibodies (ab) from the yolk of eggs of immunised chickens is more and more accepted as an useful alternative to the immunisation of mammals. The subject of this work is the immunisation of chickens with human IgG and the extraction of specific anti human IgG ab from egg yolk in order to obtain monospecific Coombs reagent. 12 Leghorn hens (2...