Antibody to rat collagen, prepared in rabbits and injected into the circulation of normal or adjuvant-prepared rats, becomes fixed to its antigen and can then be identified in tissue sections under ultraviolet light by its fluorescence after application of fluorescein-conjugated anti-rabbit globulin. In heart, lung, liver, spleen, adrenal, kidney, jejunum, lymph node, thymus, joint synovia, per...

chalcone (1,3-diarylprop-2-en-1-one) derivatives have been introduced as selective cyclooxygenase-2 inhibitors. in the present study, anti-nociceptive and anti-inflammatory effects of eight novel compounds were evaluated in male mice and wistar rats by using the writhing and formalin-induced paw edema tests respectively. the activities of the compounds were compared with celecoxib as a referenc...

Mouse hybridomas producing antibodies against structural proteins of canine distemper virus (CDV) were produced by fusion of Sp2/0 myeloma cells with spleen cells from BALB/c mice immunized with purified preparations of Vero cell-grown CDV. Ascites fluids collected after intraperitoneal inoculation with 149 CDV antibody-producing hybridoma cell lines were characterized by different serological ...

Anti-D immunoglobulin is now widely used to prevent Rh-negative mothers from being sensitized by Rh-positive fetal erythrocytes. The administration of anti-D following the transfusion of large amounts of Rh-positive erythrocytes into Rh-negative individuals has been less uniformly successful in preventing primary immunization (Bowman and Chown, 1968), and occasional mild (Woodrow et al, 1968) o...

Anti-D immunoglobulin is now widely used to prevent Rh-negative mothers from being sensitized by Rh-positive fetal erythrocytes. The administration of anti-D following the transfusion of large amounts of Rh-positive erythrocytes into Rh-negative individuals has been less uniformly successful in preventing primary immunization (Bowman and Chown, 1968), and occasional mild (Woodrow et al, 1968) o...

Antibody against cytoplasmic myosin, when microinjected into actively dividing cells, provides a physiological test for the role of actin and myosin in chromosome movement. Anti-Asterias egg myosin, characterized by Mabuchi and Okuno (1977, J. Cell Biol., 74:251), completely and specifically inhibits the actin activated Mg++ -ATPase of myosin in vitro and, when microinjected, inhibits cytokines...

The material in gamma globulin ("reactant") which reacts with rheumatoid sera in the F II precipitin and F II tanned sheep cell agglutination tests was concentrated by precipitation with sodium sulfate. The concentrated "reactant" appeared to consist of polydispersed molecular aggregates of gamma globulin with s(20) constants as high as 40, as well as the previously described inhomogeneous aggr...

Introductio n. Coronavirus infection is an acute viral disease with a predominant lesion of the upper respiratory tract caused by RNA-containing virus Coronaviridae family. However, it known that neutralizing antibodies play important role in antiviral therapy because they effectively inhibit reproduction viruses and reduce severity disease. Polyclonal contained convalescent plasma are usually ...

Varicella is usually benign exanthematous disease, which primarily affects children. The common complications are bacterial infection of skin eruptions, pneumonia, cerebellar ataxia, hepatitis, thrombocytopenia and arthritis [1]. Autoimmune hemolytic anemia (AIHA) is a rare complication of varicella and only few cases are reported [2-5]. Overall the incidence of AIHA in children is as low as 0....